In total hip arthroplasty, wear particles generated at articulating surfaces and interfaces between bone, cement and implants have a negative impact on osteoblasts, leading to osteolysis and implant loosening. The aim of this experimental study was to determine the effects of particulate wear debris generated at the interface between straight stainless steel hip stems (Exeter(®)) and three diff...

The introduction of silver, either in the liquid phase (as silver nitrate solution: Ag(L)) or in the solid phase (as silver phosphate salt: Ag(S)) of calcium carbonate-calcium phosphate (CaCO3-CaP) bone cement, its influence on the composition of the set cement (C-Ag(L) and C-Ag(S) cements with a Ca/Ag atomic ratio equal to 10.3) and its biological properties were investigated. The fine charact...

Acrylic bone cements have been used for about 40 years to fix artificial prosthesis to bone structure. The properties of the acrylic bone cement mostly depend on the characteristics of the beads, which are the main component of the solid part of the cement. In this work beads of poly(methyl methacrylate-co-styrene) were synthesized by suspension polymerization. The objective of this study was t...

Optimization of an acidic calcium phosphate cement with enhanced radiopacity. INTRODUCTION: Calcium phosphate cements (CPCs) are commonly used in biomedical applications due to their resemblance to the mineral phase of bone. However, due to this resemblance the radiopacity of CPC is very similar to that of bone. The inorganic radiopacifiers (e.g. ZrO 2 and BaSO 4) commonly used in non degradabl...

Introduction: Injectable bone cements based on calcium sulfate and calcium phosphate are potential materials for bone void fillers. Calcium sulfate has been used for many years to produce materials for bone augmentation, and it continues to be the object of interest and research, because the calcium sulfate can be injected like a bone cement material into irregularly shaped bony defects. But th...

Bone cements loaded with combinations of antibiotics are assumed more effective in preventing infection than bone cements with gentamicin as a single drug. Moreover, loading with an additional antibiotic may increase interconnectivity between antibiotic particles to enhance release. We hypothesize addition of clindamycin to a gentamicin-loaded cement yields higher antibiotic release and causes ...

Background & Aims: Treatment of osteoporotic distal radius fracture with metaphyseal defect is often complicated by secondary displacement, because of posterior cortex comminution. The aim of this study was to investigate functional outcomes and advantages of injection of bone cement in stabilizing and maintaining this fracture reduction. Methods: This prospective study was performed on 20 ...

The genesis and evolution of acrylic bone cement. Otto Röhm is known as the developer of polymethylmethacrylate PMMA in 1901. Preparation and Characterization of Injectable Brushite. Filled-Poly Methyl Methacrylate Bone Cement. Rodriguez 1, Jonathan Chari.Bone cement implantation syndrome. 1Department of Anaesthesia, University Hospital of. Problems with modern bone cements such as the loosenin...

Acrylic bone cements are widely used for fixation of joint prostheses as well as for vertebral body augmentation procedures of vertebroplasty and balloon kyphoplasty, with the cement zone(s) being subjected to repeated mechanical loading in each of these applications. Although, in vertebroplasty and balloon kyphoplasty, the cement zone is exposed to mainly cyclical compressive load, the compres...

Nowadays in orthopedic surgery -in the treatment of bone and soft tissue infectionsthere is an increasing claim for improving biodegradable drug delivery systems that can be easily placed into the site of application instead of the currently applied polymethylmethacrylate (PMMA) bone cements, since PMMA has some undesirable side effects. Therefore the aim of the study was to develop an injectab...