Mediastinal Myeloid Sarcoma is a rare entity. Here we present case of 28-year-old gentleman, who first presented with mediastinal mass and was clinically considered lymphoblastic lymphoma. He diagnosed initially as having T lymphoma on trucut biopsy. After one month patient Acute myeloid leukemia peripheral smear bone marrow examination confirmed the help flow cytometry. The biopsy slides from ...

Bone marrow examination is commonly used in the evaluation of hemato-oncological disorders and in patients with cancer of solid organs to detect metastases. This study reviews clinical, hematological and pathological data of nine cases with bone marrow metastases from solid tumors. The significance of bilateral bone marrow aspirations and biopsy has also been highlighted. Out of 784 bone marrow...

OBJECTIVE The frequency of bone marrow infiltration by Hodgkin lymphoma is low and varies from 3 to 18%. Hence there exists a dilemma whether bone marrow staging should be done only in the high risk cases. This study aims to study the clinicopathological features and the histomorphology of bone marrow infiltration by Hodgkin Lymphoma. MATERIAL AND METHOD Bone marrow aspirates and biopsies fro...

OBJECTIVE To report a case of arteriovenous fistula (AVF) following bone marrow aspiration and trephine biopsy. CLINICAL PRESENTATION AND INTERVENTION A 76-year-old man was diagnosed with acute myeloblastic leukemia. Pain and hematoma were detected in his left leg and hip 4 days after bone marrow aspiration and trephine biopsy. A pelvic arteriography was performed, and a diagnosis of AVF was ...

A 23-year-old man presented to our clinic for a second opinion. He was given the diagnosis of myelodysplastic syndrome (MDS) years prior, based on a history of iron overload and bone marrow biopsy findings of a hypercellular marrow with erythroid hyperplasia and dysmegakaryopoiesis. Further history revealed intermittent jaundice and scleral icterus. His physical examination was notable for shor...

AIMS To evaluate the use of methyl methacrylate resin as an embedding medium for undecalcified bone marrow trephine biopsy specimens. METHODS About 2500 undecalcified bone marrow trephine biopsy specimens were processed, and embedded in methyl methacrylate resin. Semithin sections (2-3 microns) were stained by routine tinctorial and immunocytochemical staining methods with a wide range of ant...

AIMS To investigate the value of bone marrow biopsy in the diagnosis of mycobacterial infection. METHODS The culture results of 433 bone marrow samples taken between 1983 and 1992 were reviewed. The histopathology reports on bone marrow trephine specimens of culture positive samples and all those on HIV positive patients sent in 1992 were also reviewed. RESULTS Fifty one specimens yielded M...

Bone marrow aspiration is useful in making out better individual cell morphology. Whereas biopsy is useful in bone marrow architectural pattern and distribution. 2 Bone marrow aspiration always give important information of reaction of hemopoietic tissue in various condition in adition to findings of blood sample as the bone marrow can be affected by both hematological and non haematological di...

Accurate detection of bone marrow involvement in patients with lymphoma is of crucial importance because of the prognostic and therapeutic consequences. Bone marrow trephine biopsy (BMB) is currently regarded as the method of choice for the evaluation of the bone marrow in lymphoma, but it is invasive, has a risk of complications, and lacks sufficient sensitivity due to the possibility of sampl...

Bone marrow aspiration (BMA) and bone marrow trephine biopsy are important procedures for the diagnosis of hematological malignancies and nonmalignant diseases in children. During BMA, bone marrow particles are obtained for analysis including microscopic morphologic evaluations and differential counts. During a trephine biopsy, a core of bone marrow is obtained and processed for the evaluation ...