Osteoporosis is frequently associated with Ankylosing Spondylitis (AS). Bone mineral density (BMD) decreased predominantly in patients with active disease. Moreover, conventional therapy, i.e. NSAID seems to have no influence in the bone loss. It has been suggested that local or systemic inflammatory cytokine release might be implicated in bone loss. Monoclonal antibody to TNFalpha in patients ...

The genetic bases of peak bone mass determinants are still poorly understood, particularly in males. We investigated the relationship between vitamin D receptor (VDR) 3'- and 5'-gene polymorphisms (as determined by the restriction enzymes BsmI and FokI) and bone mineral mass, and calcium and inorganic phosphate (Pi) metabolism in an homogeneous cohort of young healthy men. In 104 healthy subjec...

BACKGROUND Osteoporosis is a serious global health problem for the future, that is why improving diagnostic methods and prevention of this disease could be helpful. OBJECTIVES To assess the effects of calcium supplementations combined with Vitamin D on bone mineral density (BMD) and bone mineral content (BMC) in a representative sample of peri- and post-menopausal women in a double-blind, a r...

BACKGROUND Studies from high income countries (HIC) have generally shown higher osteoporotic fracture rates in urban areas than rural areas. Low bone mineral density (BMD) increases susceptibility to fractures. This review aimed to assess whether urbanicity is consistently associated with lower BMD globally. METHOD Ovid MEDLINE, EMBASE, and Global Health (-April 2013) were searched for articl...

background: the aim of the present study was to evaluate the relationship between the bone density of various regions of jaws and skeletal bones. materials and methods: a total of 110 patients with a mean age of 55.01 ± 10.77 years were selected for the purpose of the present descriptive study. dual x-ray energy absorptiometry (dxa) was carried out to determine bone mineral density (bmd) of the...

PURPOSE The traditional belief that obesity is protective against osteoporosis has been questioned. Recent epidemiologic studies show that body fat itself may be a risk factor for osteoporosis and bone fractures. Accumulating evidence suggests that metabolic syndrome and the individual components of metabolic syndrome such as hypertension, increased triglycerides, and reduced high-density lipop...

OBJECTIVE The main aim of this study was to explore the relationship between fat mass index and hip bone mineral density in a group of Lebanese adolescents and young adults. METHODS & RESULTS 91 females and 111 males (aged 13 to 30) participated in this study. Body composition (lean mass, fat mass and bone mineral content) and bone mineral density (BMD) of whole body (WB), total hip (TH) and ...

background: the purpose of this study was to evaluate long-term changes in bone density profile among survivors of childhood acute lymphoblastic leukemia. patients and methods: this was a 5 year prospective study comprised of thirty-one survivors of childhood acute lymphoblastic leukemia with a mean age of 11.8 (4.6) years, who completed therapy at least 1 year previously (according to the all-...

Background: Exercise can reduce osteoporotic fracture risk by strengthening bone or reducing fall risk. Falls prevention exercise programmes can reduce fall incidence, and also include strengthening exercises suggested to load bone, but there is little information as to whether these programmes influence bone mineral density (BMD) and strength. Objective: To evaluate the skeletal effects of hom...