Bone Regeneration In article number 2200298 by Wenguo Cui, Guochun Zha, Dechun Geng, and co-workers, a kind of lithium-based bioglasshydrogel is implanted in femoral defect diabetic rats. Photo-crosslinked hydrogel triggered blue light releases Si4+, Li+ other ions to promote osteogenesis, angiogenesis anti-inflammation. This work represents the delightful approach orchestrating bone regenerati...

Bone Regeneration In article 2201548 by Zhijian Xie, Jue Shi, and co-workers, a scaffold is designed based on the biomimetic mineralization theory, containing ultra-small particle size calcium phosphate nanoclusters (UsCCPs) with their 1–2 nm size. It can enhance bone strength characteristics promoting intrafibrillar promote M2 type polarization of macrophages, thus forming an immune microenvir...

Mandibular defects may result from many conditions such as trauma, inflammatory diseases and tumors. There are rare cases reported in the literature that have demonstrated spontaneous bone regeneration after resection of the mandible. Several factors such as age, preservation of the periosteum and genetics seem to influence spontaneous bone regeneration capacity in individuals. Evaluation of th...

Bone regeneration has been extensively studied over the past several decades. The surgically‑induced mouse model is the key animal model for studying bone regeneration, of the various research strategies used. These mouse models mimic the trauma and recovery processes in vivo and serve as carriers for tissue engineering and gene modification to test various therapies or associated genes in bone...

Watkins, Lauren E. M.S.B.M.E., Purdue University, May 2016. Densified Collagen-Fibril Biomaterials for Bone Tissue Engineering. Major Professor: Sherry Voytik-Harbin. Millions of craniofacial bone defects occur annually as a result of trauma, congenital defects, disease, or tooth extraction1, 2. When present in the oral cavity, these defects are associated with adverse impacts on speech, mastic...

  Background and Objective: The concept of immediate occlusal loading with dental implants offers several advantages. In this research, the effect of type of restoration on Osseointegration rate of dental implants was histologically evaluated. Materials and Methods: Three months prior to implantation, the lower premolar teeth of 15 dogs were extracted. Then, 3 to 4 Maestro™ implants were plac...

Introduction: Beta calcium sulfate hemihydrate (BCSH), which is commonly known as “Gypsum plaster” has long been used as bone graft material because of its excellent biocompatibility and the ability for bone regeneration. Several methods have been used for the preparation of BCSH, including heat treatment of calcium sulfate dihydrate with water, application of inorganic acids or condensed inorg...

In regenerative approaches, scaffolds play a crucial role in defining the 3-D anatomical shape and microenvironment for cells, while maintaining space, favoring regeneration of new bone, preventing soft tissue migration bony lesion. A variety materials have been explored as bone regeneration. Metals are generally inappropriate such applications because they lack desired degradability biological...

background: it has been stated that the bone allografts from different tissue banks may lead to various amount of bone induction, so the aim of this study was to evaluate bone regeneration of three demineralized allografts both histologically and histomorphometrically in rabbits calvaria bone defects. materials and methods: in this double-blind randomized experimental animal study, 32 critical ...

introduction : efforts are being made to improve the efficacy of biomaterials used as bone substitutes for bone regeneration in the oral and maxillofacial region. graft materials have been recently produced in iran; however, studies are required to confirm their efficacy. this study aimed to compare the histomorphometric results of using mineralized allografts produced by the hamanandsaz baft k...