Background Despite decades of extensive research, bovine respiratory disease (BRD) remains the most devastating in beef cattle production. Establishing a clinical diagnosis often relies upon visual detection non-specific signs, leading to low diagnostic accuracy. Thus, post-weaned are metaphylactically administered antimicrobials at facility arrival, which poses concerns regarding antimicrobial...

BACKGROUND Bovine respiratory disease (BRD) is caused by growth of single or multiple species of pathogenic bacteria in lung tissue following stress and/or viral infection. Next generation sequencing of 16S ribosomal RNA gene PCR amplicons (NGS 16S amplicon analysis) is a powerful culture-independent open reference method that has recently been used to increase understanding of BRD-associated b...

Concerns are growing over the impact of livestock farming on environment and public health. The livestock industry is faced with the double constraint of limiting its use of natural resources and antimicrobials while ensuring its economic sustainability. In this context, reliable methods are needed to evaluate the effect of the prevention of endemic animal diseases on the productivity of livest...

BACKGROUND Bovine respiratory disease (BRD) is a major problem in veal calf rearing units. The objective of this randomised clinical trial was to assess the effectiveness of tildipirosin as a metaphylactic treatment in veal calves on the number of BRD treatments, lung consolidation on thoracic ultrasonography (TUS) and average daily gain (ADG). A total of 209 veal calves from a pre-weaning fatt...

Traditionally, route discovery in MANETs operates in unilateral (source-initiated) manner. We propose a new scheme called bilateral route discovery (BRD), where both source and destination actively participate in a route discovery process. BRD has the potential to reduce the control overhead by one half. As an underlying protocol for BRD, we propose gratuitous route error reporting (GRER) to no...

Nitric oxide (NO) generated by neutrophils (PMN) is involved in tissue damage in the course of respiratory inflammation. However, little is known about participation of IL-8 in NO mediated lung injury in the course of Bovine Respiratory Disease (BRD). The purpose of this study was to evaluate how IL-8 influenced the generation of NO by neutrophils isolated from heifers in the course of acute an...

Recently, researchers have explored to provide a queue management scheme with differentiated loss guarantees for the future Internet. The Bounded Random Drop (BRD), known as the best existing scheme, is one of such efforts which guarantees strong loss differentiation to the level of traffic in the different service classes. Even though BRD has several benefits such as low complexities and good ...

The usual means of assessing the health of newly received beef cattle susceptible to bovine respiratory disease (BRD) are subjective, typically involving visual evaluation aided by minimal clinical measurements. Recent evidence based on the occurrence of pneumonic lung lesions at slaughter indicates a need for more accurate methods of diagnosing BRD. Inadequate passive immune transfer at birth ...

The performance of a manufacturing or logistic system is determined by its constraints. Therefore, in order to improve the performance, it is necessary to improve the constraints, also known as the bottlenecks. Finding the bottlenecks, however, is not easy. This paper compares the two most common bottleneck detection methods, based on the utilization and the waiting time, with the shifting bott...

In order to obtain data concerning the involvement of Mannheimia haemolytica in bovine respiratory disease (BRD) outbreaks, a serological survey was carried out on paired (acuteconvalescent) sera from 1310 beef and 810 dairy cattle collected in 262 BRD outbreaks in Italian herds during 2002-2006. No vaccination program to M. haemolytica A1 was applied in the investigated herds. For each outbrea...