The extraction of lutein and β-carotene from spinach (Spinacia oleracea L.) leaves is important to the dietary supplement industry. A Box-Behnken design and response surface methodology (RSM) were used to investigate the effect of process variables on the ultrasound-assisted extraction (UAE) of lutein and β-carotene from spinach. Three independent variables, extraction temperature (°C), extract...

INTRODUCTION Nanoparticulate carrier system was used to target, improve bioavailability, control the drug release and avoid the enzymatic degradation. Among the nanoparticulates i.e. SLNs are attractive and face the challenges of stability. The major obstacle with the SLNs was agglomeration in order to avoid this problem freeze drying was attempted. In this laboratory process which involves fre...

In this study, Box-Behnken”s Response Surface Methodology (RSM) was applied to study the esterification reaction effectiveness of acid activated Ngbo clay catalyst. The were monitored based on process conditions temperature, duration, amount reactant, catalyst weight and particle size. Box--Behnken’s indicates that clay-catalysed reactions proceed through dual mechanisms Acid-complex Alcohol-co...

‎Application of Box-Behnken Design and Response Surface Methodology Acid Red 18 Adsorption onto PAC‎ (Synthesized Carrot Waste) Coated with Fe3O4 Nanoparticles from Aquatic Solution: Kinetic Isotherm Studies

Purpose: To study the effect of some factors on the size of finasteride nano-emulsion by chemometric approach which could predict the size of nano-emulsion droplets under different conditions. Methods: Nano-emulsions were prepared using spontaneous emulsification method which occurs when organic and aqueous phases are mixed. The organic phase was a homogeneous solution of oil (finasteride as a ...

The main objective of this paper is to optimize biosurfactant production by Pseudomonas aeruginosa 2297 with statistical approaches. Biosurfactant production from P. aeruginosa 2297 was carried out with different carbon sources, and maximum yield was achieved with sawdust followed by groundnut husk and glycerol. The produced biosurfactant has showed active emulsification and surface-active prop...

While chiral 2,3-Butanediol (2,3-BD) is currently receiving remarkable attention because of its numerous industrial applications in the synthetic rubber, bioplastics, cosmetics, and flavor industries, 2,3-BD-mediated feedback inhibition of Paenibacillus polymyxa DSM 365 limits the accumulation of higher concentrations of 2,3-BD in the bioreactor during fermentation. The Box-Behnken design, Plac...