Lung transplantation is the only effective treatment option for patients with end-stage lung disease. However, donor organ shortage makes timely transplant not possible for all patients, especially in Korea. We investigated the number and utilization of donor lungs by retrospectively reviewing all donor organs registered in the Korea Network for Organ Sharing database from March 2012 to March 2...

In recent time the critique of whole brain death as criterion human death, that was introduced in 1968, has been growing. The paper aims to show systematically there are good reasons based on empirical findings combined with Thomistic Christian anthropology accept traditional cardiopulmonary death. This will be shown through a systematic other criteria death: higher stem and controlled cardiac/...

Background/Introduction Non-heart-beating donation, in the situation where a patient cannot be diagnosed as dead using brainstem criteria, may be an alternative to overcome shortage of donors. Preclinical studies showed that functional recovery of hearts after circulatory determination of death (DCDD) were similar to that of hearts from brain-dead donor. However, there are several experimental ...

background when using brain dead donors for organ donation, assessment of kidney function before the procedure is essential. objectives it would be ideal to find an early marker of viability of donor kidneys that is more accurate than creatinine. patients and methods the present study was conducted from march of 2011 to march of 2012, included 52 deceased donors. serum and urinary neutrophil ge...

brain death is associated with increased inflammatory cytokines levels and poor graft quality to transplant. we aimed to evaluate the impact of ascorbic acid (aa) on the inflammatory status of brain-dead donors (bdds). forty bdds were randomly divided into two groups. donor treatment (n=20) consisted of 100 mg/kg aa infusion 6 hours before donor operation and subsequent infusion of 100 mg/kg/p6...

A b st ra ct In recent years, transplantation has assumed an important role in the treatment of patients with end-stage organ failure. With the passage of Transplantation of Human Organ Act by the Indian parliament, transplantation of organs from brain dead donors has become a reality. Although there are many issues in success of cadaver programme, intensivists can play a crucial role by conver...

Islet quality loss after isolation from brain-dead donors still hinders the implementation of human islet transplantation for treatment of type 1 diabetes. In this scenario, systemic inflammation elicited by donor brain death (BD) is among the main factors influencing islet viability and functional impairment. Exendin-4 is largely recognized to promote anti-inflammatory and cytoprotective effec...

Background & Aims: At present due to brain dead patients’ families refuse to organ donation, the number of available organs is less than the requesting cases. The aim of this comparative descriptive study was to compare opinions of donor and nondonor families about relevant factors in their decision making. Methods: participants included 175 members of 71 families (141 members of 56 donor famil...