Nonneoplastic demyelinating processes of the brain with mass effect on magnetic resonance imaging can cause diagnostic difficulties. It requires differential diagnosis between the tumefactive demyelinating lesion and the coexistence of neoplasm. We document the case of 41-year-old woman with clinical and radiological findings suggestive of multiple sclerosis. Additional investigations confirmed...

PURPOSE To describe the clinical, neurodiagnostic, and MR findings in seven children with brain stem and spinal multiple sclerosis. METHODS Spinal or brain stem multiple sclerosis was diagnosed in seven children between 1986 and 1992. All patients had neurologic and MR examinations as well as neurodiagnostic testing, including spinal fluid analysis and brain stem and auditory evoked potential...

A 54-year-old woman presented to the emergency room with 3 months of slurred speech, language problems, and right hemiparesis. Initial impression based on history, exam, and imaging was brain abscess vs. primary or metastatic neoplasm. Brain biopsy of the lesion and pathologic specimens were obtained. Below is a description of her presentation, hospital course, imaging, and pathology, as well a...

Intractable fever in cancer patients is problematic and the causes of this fever can be diverse. Paroxysmal persistent hyperthermia after sudden mental change or neurologic deficit can develop via autonomic dysregulation without infection or any other causes of fever. Paroxysmal hyperthermic autonomic dysregulation is a rare disease entity. It manifests as a form of paroxysmal hypertension, fev...

results: among 11 patients who underwent surgery consisted of eight males and three females. their metastasis originated from testis tumors (n = 5), renal cell carcinoma (rcc; n = 4), bladder tumor (n = 1), and prostate cancer (n = 1). their mean age was 41.27 years (range, 21-67). the mean age of the patients with rcc and testis tumor at the time of diagnosing metastasis was 54 and 24.8 years,...

background: choriocarcinoma is a rare highly malignant trophoblastic neoplasm. it can be preceded by any form of gestation including a complete or a partial mole, miscarriage and normal pregnancy. simultaneous intraplacental choriocarcinoma involving both mother and infant is extremely rare. hepatomegaly, anemia, elevated ßhcg is the diagnostic triad. here we report a 6 weeks old afghan girl in...

The anaplastic oligodendrogliomas are uncommon gliomas. It is clinically significant to know this entity as they have unique clinical, histopathological and molecular features. We present a 43 year female having complaint of headache, tingling numbness, giddiness. Which was 2 duration, off on, increased in last 15 days. MRI brain (plain + contrast) showed large heterogenously enhancing cortical...

The malignant melanoma is a neoplasm associated with a wide variety of cutaneous paraneoplastic syndromes, as dermatomyositis, systemic sclerosis, paraneoplastic pemphigus. We describe a case of four multiple trichilemmal cystis arising on frontal region in the same patient with brain metastasis and unknown primary melanoma and discuss their relationship.