BACKGROUND Partial volume effects in atrophied areas should be taken into account when interpreting brain perfusion single photon emission computed tomography (SPECT) images of neurodegenerative diseases. To evaluate both perfusion and atrophy using brain SPECT alone, we developed a new technique applying tensor-based morphometry (TBM) to SPECT. METHODS After linear spatial normalization of b...

BACKGROUND AND PURPOSE Tinnitus is associated with an increased activity in central auditory system as demonstrated by neuroimaging studies. Brain perfusion scanning using single photon emission computed tomography (SPECT) was done to understand the pattern of brain blood perfusion of tinnitus subjects and find the areas which are mostly abnormal in these patients. MATERIALS AND METHODS A num...

INTRODUCTION. Many approaches have been applied to evaluate brain perfusion in neonates: brain ultrasound, near-infrared spectroscopy, and positron emission tomography (PET). However perfusion weighted imaging (PWI) MRI has been shown to enable in vivo direct measurements of brain perfusion in different brain regions. Recent advances have lead to the development of non-contrast agent based Arte...

Spontaneous Intracranial Hypotension (SIH) is usually due to cerebrospinal fluid (CSF) leak, resulting in loss of CSF volume. Posterior reversible encephalopathy syndrome (PRES) the inability posterior circulation brain autoregulate response significant variation blood pressure. Altered perfusion with associated blood-brain barrier disruption may lead vasogenic edema, without infarction, common...

BACKGROUND AND PURPOSE Color-coded perfusion maps can be calculated from ultrasound harmonic gray-scale imaging data to analyze brain tissue perfusion. METHODS In 13 healthy volunteers, 2 doses (0.5 and 1.5 mL) of Optison, a perfluoropropane-containing ultrasound contrast agent, were injected intravenously, and they produced a strong increase in echo enhancement in the brain parenchyma. The c...

Oxygen metabolism is a key factor in the life of living organism. The article first part review methods for measuring oxygen metabolism. Purpose. aim this to present an insight into evolution way from global local measurement brain perfusion. role 15 O isotope as “gold standard” using positron emission tomography (PET) described. We also provide case report tumor perfusion measurements our clin...

BACKGROUND The syndrome of the sinking skin flap (SSSF) with delayed sensorimotor deficits after craniectomy is not well known and often neglected. Among various postulated causes, there is evidence that disturbed brain perfusion may be related to the observed symptoms, and that cranioplasty reliably alleviates these symptoms. We report a case of sinking skin flap syndrome (SSFS) with recovery ...

PURPOSE To assess spatiotemporal patterns of local perfusion in MR brain perfusion images for patients with unilateral carotid stenosis. MATERIALS AND METHODS MR perfusion images acquired from 12 patients with unilateral carotid stenosis were retrospectively segmented using independent component analysis. Regions of interest selected from the segmentation results were used to measure the time...