introduction: intraoperative radiation therapy device (iort) is one of the several options for partial breast irradiation. iort is sent to the tumor bed during surgery and can be replaced with conventional standard therapy (ebrt). the aim of this study was to evaluate the safety and effectiveness of iort machine compared with ebrt and to determine the dominant option in terms of the cost-effect...

BACKGROUND High dose-rate Intra-Operative Radiation Therapy (HD-IORT) is used to provide effective local control for patients with high-risk locally advanced or recurrent tumors. However, the utility of HD-IORT for patients with bladder cancer has not been studied. OBJECTIVE To characterize our institutional experience with HD-IORT in patients with cancer requiring genitourinary surgery, in a...

Background/aim: Intraoperative radiation therapy (IORT) may pose a risk for wound complications. All technical aspects of IORT regarding early wound complications were evaluated. Materials and methods: Ninety-three consecutive patients operated on with the same surgical technique and given (study group) or not given (control group) IORT were included. Wound complications were evaluated in two g...

After standard treatment of primary breast cancer, local relapse can develop in a previously irradiated region. The decision to refer a patient for a second radiotherapy must be thoroughly evaluated due to the increased risk of side effects. We report a case of a 43-year-old Caucasian female with a history of left breast lumpectomy and radiation treatment in 1990 for an invasive ductal carcinom...

Purpose Intraoperative radiation therapy (IORT), delivered by intraoperative electron beam (IOERT) or high-dose-rate brachytherapy (HDR-IORT), may reduce the local recurrence rate in patients with locally advanced and recurrent rectal cancer (LARC LRRC, respectively). The aim of this study was to compare oncological outcomes between both IORT modalities LARC LRRC who underwent a microscopic irr...

Literature was reviewed to assess the physical aspects governing the present and emerging technologies used in intraoperative radiation therapy (IORT). Three major technologies were identified: treatment with electrons, treatment with external generators of kV X-rays and electronic brachytherapy. Although also used in IORT, literature on brachytherapy with radioactive sources is not systematica...

BACKGROUND Patients with locally advanced or recurrent rectal cancer often require multimodality treatment. Intraoperative radiation therapy (IORT) is a focal approach which aims to improve local control. METHODS We retrospectively reviewed 42 patients treated with IORT following definitive resection of a locally advanced or recurrent rectal cancer from 2000-2009. All patients were treated wi...

Chicago, said her center has been doing Iort with an Intrabeam for nearly a year and has treated about 50 patients so far. “We don’t have a strict protocol,” she said, “but we tend to use it on women in their 60s who have relatively small, invasive [ductal] cancers.” “Patients love it,” said hansen. But it’s frustrating for those who find out later, from the final pathology report, that they ha...