Abstract Imidazolium salts have always been well recognized as the precursors to ionic liquids. Various studies extended their biological properties, in which many discovered interesting results. In this study, a series of pyridine‐functionalized (benz)imidazolium were synthesized using conventional synthetic method, and microwave irradiation. The products tested biologically against list micro...

Solanum torvum Sw. is a native plant of India found abundantly in North East. It has many medicinal properties and its berries are used to treat fungal infections by the natives study area. The efficacy was evaluated using both vitro antimicrobial methods vivo model vaginal Candida albicans infection. Two models, disc diffusion assay micro dilution broth laboratory female rats were used. In hig...

A total of 97 anaerobic bacteria were tested for susceptibility to ampicillin, ampicillin-sulbactam, and amoxicillin-clavulanic acid by broth microdilution and disk elution methods, the results of which were compared with those of the reference agar dilution method. With the broth microdilution method, approximately 95% of MICs were within 1 dilution of those of the reference agar method, with ...

Effective treatment of bacterial infection relies on timely diagnosis and proper prescription of antibiotic drugs. The antimicrobial susceptibility test (AST) is one of the most crucial experimental procedures, providing the baseline information for choosing effective antibiotic agents and their dosages. Conventional methods, however, require long incubation times or significant instrumentation...

Broth microdilution susceptibility tests of Candida species have now been standardized by the National Committee for Clinical Laboratory Standards (NCCLS). An eight-laboratory collaborative study was carried out in order to document reproducibility of tests of Candida parapsilosis ATCC 22019 and Candida krusei ATCC 6258 by the NCCLS method. Replicate broth microdilution tests were used to defin...

The resistance of Escherichia coli to cephalothin was found to be overestimated when the Phoenix automated susceptibility system was used to determine resistance compared to reference broth microdilution, a finding that jeopardized the use of cephalexin for first-line treatment of urinary tract infections in children. In addition, using broth microdilution, we studied the accuracy of either cep...

This study was conducted to synthesize and characterize 1,3-dialkyl-5,6-dimethyl-benzimidazolium salts their silver complexes. Four novel silver(I)-N-heterocyclic carbene complexes were synthesized characterized by mass analyses, FT-IR NMR spectroscopy. The biological capacity of the compounds evaluated in vitro for antimicrobial antitumor activities. minimum inhibitory concentration (MIC) dete...

Using a set of 55 Staphylococcus aureus challenge organisms, we evaluated six routine methods (broth microdilution, disk diffusion, oxacillin agar screen, MicroScan conventional panels, MicroScan rapid panels, and Vitek cards) currently used in many clinical laboratories and two new rapid methods, Velogene and the MRSA-Screen, that require less than a day to determine the susceptibility of S. a...