Pharmacokinetic study of paracetamol was conducted in five female buffalo calves following single i.v. injection of paracetamol @ 40 mg/kg. The drug was detected up to 2 h only in plasma, while it was detected for a longer period of 48 h in urine with a mean concentration of 1.87 ± 0.48 and 10.90 ± 1.14 mg/ml, respectively. The mean distribution half life (t 1/2 α) of 0.11 ± 0.01 h and eliminat...

To evaluate different levels of energy for optimum growth in Iranian regional buffalo male calves, a completely randomized study was conducted, using 27 yearling buffalo male calves with initial live weight of 201 ± 14 kg. Three diets were formulated to provide 90%, 100%, and 110% energy level requirements equivalent to those of steers derived from NRC beef cattle recommendations and they were ...

Aim: The aim of this study was to evaluate the simple tube cystostomy procedure for management of urethral obstruction cases in ruminants. Materials and Methods: Tube cystostomy was used to treat a total of 58 ruminants, which included 35 buffalo calves and 23 goats. Diagnosis of the disease was made with the history of anuria, clinical signs, and physical examinations. Physical parameters like...

AIM To evaluate the efficacy and safety of glycopyrrolate - xylazine - propofol anesthesia in buffalo calves. MATERIALS AND METHODS The study was conducted on six clinically healthy male buffalo calves, 6-12 months of age, and weighing between 130 and 170 kg. In all the animals; glycopyrrolate (0.01 mg/kg, IM), xylazine (0.1 mg/kg, IM) and 1% propofol as single bolus (1.5 mg/kg, intravenous),...

Male Indian buffalo (Bubalus bubalis) calves were submitted to Schistosoma mansoni infection by percutaneous, oral and subcutaneous routes. No worms or eggs were found in four of the animals tested. Bubalus bubalis appears to be refractory for S. mansoni.

Pharmacokinetics and urinary excretion of an intravenous dose of 5 mg.kg-1 ofloxacin were investigated in water buffalo calves. Plasma concentrations of ofloxacin were determined by high-performance liquid chromatography. Ofloxacin was rapidly distributed from the central to the peripheral compartment as evidenced by a short distribution half-life (0.09 h ± 0.003 h) and high K12 (4.7 h(-1) ± 0....

The pharmacokinetics and dosage regimen of cefotaxime following its single subcutaneous administration (10 mg/kg) were investigated in buffalo calves. Plasma and urine samples were collected over 10 and 24 h post administration, respectively. Cefotaxime in plasma and urine was estimated by microbiological assay technique using E. coli as test organism. The pharmacokinetic profiles fitted one-co...

BACKGROUND Salmonellosis in water buffalo (Bubalus bubalis) calves is a widespread disease characterized by severe gastrointestinal lesions, profuse diarrhea and severe dehydration, occasionally exhibiting a systemic course. Several Salmonella serovars seem to be able to infect water buffalo, but Salmonella isolates collected from this animal species have been poorly characterized. In the prese...

Aim: Evaluation of combined effect of fenvalerate and nitrate on biochemical parameters in buffalo calves. Materials and Methods: Sixteen male buffalo calves were divided into four groups of four calves each. Group I receiving no treatment served as the control. Group II and III animals were orally administered with fenvalerate (1.0 mg/kg/day) and sodium nitrate (20 mg/kg/day), respectively, fo...