background and objectives: infection is the most common problem following burn injury. selection and dissemination of intrinsic and acquired resistance mechanisms increase the probability of burn wound colonization by resistant species including pseudomonas aeruginosa. multi-drug resistant pseudomonas aeruginosa has frequently been reported as the cause of nosocomial outbreaks of infection in b...

Burned patients are at risk of acquiring infection because of their destroyed skin barrier, suppression of immunity, prolonged hospitalization, and invasive therapeutic and diagnostic procedures. Most of the studies on infections in burned patients are focused on burn wound infections, while nosocomial device-associated infections in this patient group are not described well. Therefore, the aim...

BACKGROND Burn wound infections carry considerable mortality and morbidity amongst burn injury victims who have been successfully rescued through the initial resuscitation. This study assessed the prevalent microrganisms causing burn wound infections among hospitalized patients their susceptibility pattern to commonly used antibiotics and the frequency of infections with respect to the duratio...

OBJECTIVE To determine if local prophylactic application of probiotic bacteria to burn wounds will prevent death in a mouse model of burn wound sepsis. BACKGROUND Infection remains the most common complication after burn injury and can result in sepsis and death, despite the use of topical and systemic antibiotics. Pseudomonas aeruginosa is a frequently implicated pathogen. Local application ...

conclusions the current study highlights that the high level of resistance to many antibacterial agents and a gradual increase in the degree of per, oxa-10, shv and tem esbls among the majority of imipenem resistant p. aeruginosa isolated from patients with burn infection is an enormous threat in burn centers in iran. results the results showed that the majority of isolates (88%) were multi-dru...

Recently, numerous compounds have been studied in order to develop antibacterial agents, which can prevent colonized wounds from infection, and assist the wound healing. For this purpose, novel silver chloride nanoparticles stabilized with chitosan oligomer (CHI-AgCl NPs) were synthesized to investigate the influence of antibacterial chitosan oligomer (CHI) exerted by the silver chloride nanopa...

backgrond burn wound infections carry considerable mortality and morbidity amongst burn injury victims who have been successfully rescued through the initial resuscitation. this study assessed the prevalent microrganisms causing burn wound infections among hospitalized patients their susceptibility pattern to commonly used antibiotics and the frequency of infections with respect to the duration...

INTRODUCTION Fusarium spp are ubiquitous fungi recognized as opportunistic agents of human infections, and can produce severe infections in burn patients. The literature on Fusarium spp infections in pediatric burn patients is scarce. OBJECTIVES To describe the clinical and epidemiological features as well as outcome of Fusarium spp infections in pediatric burn patients. PATIENTS AND METHOD...

BACKGROUND AND PURPOSE Bacteriophages, viruses that cause lysis of bacteria, can serve as an effective tool for the control of infections, especially those caused by multiple drug-resistant organisms. Klebsiella pneumoniae is one of the most predominant pathogens associated with burn wound infections, causing considerable morbidity and mortality. This study investigated the protective effect of...

Severe trauma renders patients susceptible to infection. In sepsis, defective bacterial clearance has been linked to specific deviations in the innate immune response. We hypothesized that innate immune modulations observed during sepsis also contribute to increased bacterial susceptibility after severe trauma. A well-established murine model of burn injury, used to replicate infection followin...