.................................................................................................................................. xi THESIS ORGANIZATION.......................................................................................................... xii CHAPTER 1 General Introduction ................................................................................................. 1 CH...

In a previous study, the authors found persistent presence of acute inflammation markers such as C-reactive protein and complement factors locally in burn wounds. This persistence of acute inflammation may not only delay local burn wound healing but also have a systemic effect, for instance on the heart. Here, the effects of C1 esterase inhibitor (C1inh), an inhibitor of complement activation, ...

The transport of cefmenoxime,a cephalosporin antibiotic,into three kinds of exudates (exudate from excoriated skin,exudate from burn wounds,and burn blister fluid)from blood was studied on 37 burn patients after they were given an intravenous bolus of 50mg cefmenoxime per kg body weight.Concentrations of cefmenoxime in serum and in the above exudates or fluid were determined by bioassay.Concent...

Burn units provide a unique set of resources to patients with complex wounds, sepsis, and organ failures. This resource set is useful in a number of traumatic, infectious, and medical conditions as well. Further, many burn patients have sustained simultaneous non-burn trauma which will be managed in burn programs.

Sepsis remains the major cause of death in patients with major burn injuries. In the present investigation we evaluated the interaction between burn injuries of varying severity and preexisting distant infection. We used Gram-negative bacteria (Pseudomonas aeruginosa and Proteus mirabilis) that were genetically engineered to be bioluminescent, which allowed for noninvasive, sequential optical i...

Dear Editors, We read the article titled ‘Cleansing of wounds by tap water? An evidence-based systemic analysis’ as well as the letter ‘Cleansing of wounds by tap water? Would it be safe to use in developing countries?’ by Huang et al. and Nagoba et al. with great interest (1,2). While we agree with Huang et al. that tap water irrigation helps reduce wound colonisation and infection rates cost-...

OBJECTIVE Infections are one of the most important and potentially serious complications of burn wounds. Quantitative biopsy cultures are useful for showing that a burn wound infection is not present, but these cultures are not useful for showing that an infection is present. Swab cultures are used to diagnosis surface colonization and may not accurately reflect the organism(s) causing the woun...

9 Burns is a pervasive and oppressive basic care issue. In children, burn injuries are a major reason 10 for bleakness and mortality. The quirks in the physiology of liquid and electrolyte taking care of, 11 the vital necessity and the distinctions in the different body extends in children direct that the 12 pediatric wounds administration ought to be brought with an alternate point of view tha...

materials and methods in this study, 90 patients with second-degree burn injuries who were admitted to the yazd burn hospital were randomly divided into three equal groups. in the negative control group, the wounds were covered with sterile vaseline gauze followed by double sterile dry gauze and ultimately bandaged. in the test group, the wounds were covered by an iranian hydrogel sheet (irgel)...