Over the last two decades burn mortality rates have declined (Table I) due to the development of new treatment modalities. The advances that have led to decreased mortality rates in burn patients have evolved from ongoing research of new therapies that improve long-term outcome. In 1952, a 50 per cent total body surface area burn victimized nearly one-half of young patients under 17 years of ag...

Burn induces a sustained catabolic response which causes massive loss of muscle mass after injury. A better understanding of the dynamics of muscle wasting and its impact on muscle function is necessary for the development of effective treatments. Male Sprague-Dawley rats underwent either a 40% total body surface area (TBSA) scald burn or sham burn, and were further assigned to subgroups at fou...

We tested the hypothesis that the administration of recombinant human growth hormone (rHGH) and exercise would increase lean body mass (LBM) and muscle strength in burned children to a greater extent than rHGH or exercise separately. Children, ages 7-17 yr, with >40% body surface area burned, were randomized into groups. One group (GHEX, n = 10) participated in a 12-wk in-hospital physical reha...

We estimate future area burned in the Alaskan and Canadian forest by the mid-century (2046–2065) based on the simulated meteorology from 13 climate models under the A1B scenario. We develop ecoregion-dependent regressions using observed relationships between annual total area burned and a suite of meteorological variables and fire weather indices, and apply these regressions to the simulated me...

self-burning is the most devastating burn injur y. it is a common social and medical problem in iran. in a longitudinal prospective study, from april 2003 to march 2006, all burn patients admitted to ghotb-eddin burn hospital were enrolled in this study. suicide attempts by burning accounted for 283 (21.9%) of all burn patients admitted to the hospital. most (68.2%) of self-burning patients wer...

OBJECTIVE Two forms of recombinant growth hormone that accelerate the healing of skin graft donor sites in severely burned children were evaluated. SUMMARY BACKGROUND DATA Growth hormone has been shown to reduce wound healing times in burned pediatric patients. Through genetic engineering, several different forms have been synthesized; however, not all are marketed currently. Two forms of gro...

Hand burns predominantly affect young adults, and therefore have serious social and financial implications. In the present work, 106 patients with less than 25% body surface area burns and acute partial-thickness burned hands were managed using polyethylene bags and 1% local silver sulphadiazine (SSD) cream or moist exposed burn ointment (MEBO). Females made up 61.3% of the cases and flame burn...

Treatment with glutamine has been shown to reduce myocardial damage associated with ischemia/reperfusion injury. However, the cardioprotective effect of glutamine specifically after burn injury remains unclear. The present study explores the ability of glutamine to protect against myocardial damage in rats that have been severely burned. Seventy-two Wistar rats were randomly divided into three ...

OBJECTIVE To assess the psychometric properties of the Child Stress Disorders Checklist (CSDC), a 36-item observer-report instrument that measures acute stress and posttraumatic symptoms in children. METHOD The CSDC was administered to parents of 43 children with acute burns and 41 children who had experienced a traffic crash. This instrument was also administered to the burned children's pri...