نتایج جستجو برای: c bcl 2 proto oncogene
تعداد نتایج: 3252614 فیلتر نتایج به سال:
medullary thyroid carcinoma (mtc) occurs in both sporadic (75%) and hereditary (25%) forms. the missense mutations of the rearranged during transfection (ret) proto-oncogene in mtc development have been well demonstrated. the aim of this study was to investigate frequency of g691s/s904s haplotype in mtc patients and their relatives.in this research 293 participants were studied, including 181 p...
Expression of the bcl-2 proto-oncogene on chromosome 1 8 is deregulated by the 14; 18 chromosomal translocation, an abnormality that is consistently associated with follicular non-Hodgkin’s lymphomas (NHL). Because bcl-2 is believed to function by prolonging cell survival rather than by increasing proliferation, the presence of t(l4; 18) in Hodgkin’s disease (HD) would have profound implication...
To test whether the product of the bcl-2 proto-oncogene blocks clonal deletion of self-reactive B cells, we have generated transgenic mice carrying the bcl-2 gene and the immunoglobulin genes for the anti-erthrocyte 4C8 antibody. In these transgenic mice, donal deletion of self-reactive immature B cells in the bone marrow was not inhibited in spite of expression of the bcl-2 gene. In contrast, ...
To test whether the product of the bcl-2 proto-oncogene blocks clonal deletion of self-reactive B cells, we have generated transgenic mice carrying the bcl-2 gene and the immunoglobulin genes for the anti-erythrocyte 4C8 antibody. In these transgenic mice, clonal deletion of self-reactive immature B cells in the bone marrow was not inhibited in spite of expression of the bcl-2 gene. In contrast...
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