Calcifying odontogenic cyst is considered as a rare lesion and accounts for 1% of jaw cysts. It represents a heterogeneous group of lesions which exhibit a variety of clinicopathologic and behavioral features. It has been categorized as cyst and neoplasm. Even after several classification and subclassification, COC remains an enigma. WHO classification 2005 has reclassified the lesion as calcif...

Calcifying odontogenic cyst is a developmental odontogenic cyst first described by Gorlin in 1962. It is considered as an extremely rare condition and shows extensive diversity in its clinicopathological appearances and biologic behavior. In this report a rare case of calcifying odontogenic cyst with ameloblastic proliferation (an extremely rare histologic variant) with one year follow – up is ...

The calcifying epithelial odontogenic tumor (CEOT) is a rare benign odontogenic neoplasm that accounts for approximately 1% of all odontogenic tumors. Its origin is controversial as well as its true malignant potential. A case of an advanced CEOT associated with an impacted right second molar in the mandible of a young black female patient is presented. Computed tomography imaging, radiographic...

Although rare, hard tissue deposits, namely dystrophic calcifications and cartilage, have been reported to occur in the connective tissue wall of the odontogenic keratocyst. However, dentinoid formation has not been previously documented. A case involving the left mandibular premolar-molar region in a 37-year-old Malay male is described here along with a brief review on the reported prevalence ...

Calcifying epithelial odontogenic tumor is rare. It may mimic both a non-odontogenic or odontogenic tumour causing expansion and destruction of the involved bones. Histopathology is the main stay for definitive diagnosis. Treatment options vary from enucleation to hemi mandibulectomy or maxillectomy followed by reconstruction. We present a young female patient with CEOT in an attempt to create ...

Ghost cell odontogenic carcinoma (GCOC) is an exceptionally rare and malignant odontogenic tumor with aggressive growth characteristics. We describe a case of GCOC which was considerably derived from a previously resected calcifying cystic odontogenic tumor (CCOT). Cellular atypia, mitotic activity, Ki-67 labeling index and matrix metalloprotease-9 positive expression rate were all increased in...

Calcifying cystic odontogenic tumor (CCOT) is defined as an odontogenic cyst-like benign neoplasm that characteristically contains several ghost cells, ameloblastoma-like epithelium, and occasional calcification. Ghost cell odontogenic carcinoma (GCOC), a malignant form of CCOT, is an exceptionally rare malignant tumor. In this report, we present a case of a 53-year-old man whose chief complain...

Received on: Feb 3, 2012 – Accepted on: Aug 3, 2012 ABSTRACT The calcifying cystic odontogenic tumor normally presents as a painless, slow-growing mass, involving both maxilla and mandible, primarily the anterior segment (incisor/canine area). It generally affects young adults in the third to fourth decades, with no gender predilection. Computerized tomography images revealed important characte...

Calcifying cystic odontogenic tumor (CCOT) previously known as calcifying odontogenic cyst (COC) is a relatively rare lesion. It was first reported as a separate pathologic entity by Gorlin et al in 1962 as a likely analog of the cutaneous calcifying epithelioma of Malherbe or pilomatricoma. Because of the diverse clinicohistologic features and the various neoplastic potential, there have been ...

AIM To reevaluate all cases previously diagnosed as calcifying odontogenic cyst (COC) from the archives of the Department of Oral Pathology at Mashhad Faculty of Dentistry from 1978 to 2008. MATERIALS AND METHODS Clinical histories and microscopic slides of all cases diagnosed as COC were reviewed and analyzed statistically. The information about patients such as age, sex, clinical features, ...