Diltiazem, a calcium channel blocker was studied to observe its effects on the acetylcholine contractile responses of isolated frog rectus abdominis muscle. This response was modified in a dual manner i.e., initial potentiation, followed by inhibition. Diltiazem may not have anticholinesterase like mechanism, as it potentiated the responses to both acetylcholine and succinylcholine. Rectus musc...

Previous studies have indicated that the deposition of uranium in bone is a surface-limited reaction involving an exchange of the uranyl ions of the solution for some ion in the surface of the mineral phase of bone, probably calcium (1, 2). As a further test of the exchange hypothesis, a series of ion competition experiments was conducted, in which the effects of varying concentrations of hydro...

In this research Calcium fluoride nanoparticles and its different amount of cerium ion dopant (5%and 10%) were prepared. The mentioned nanoparticle were studied by fourier transform infrared spectroscopy (FTIR) , X-ray diffraction (XRD), absorption and photoluminescence spectra (PL) and Scanning electron microscopy (SEM). The XRD patterns indicate a typical cubic fluorite structure and no other...

Calcium ion acts as an intracellular messenger of various types of extracellular signals including hormones, neurotransmitters, cytokines and growth factors. Recent advances in the research of the calcium messenger system have provided informations as to the structure and function of many proteins involved in the messenger system. Also, technical advances in the measurement of the dynamics of c...

The effects of monovalent cations on the active calcium-accumulating ability of cardiac sarcoplasmic reticulum were assessed. Grana prepared in an ion-free system accumulated calcium when ATP and Mg(++) were present. Sodium ion and to a lesser extent lithium but not K(+) reduced the amount of calcium taken up. The reduction of calcium binding by Na(+) is not due to inhibition of uptake but to a...

Calcium ion induces rapid depolymerization of microtubules, and the mechanism of interaction of Ca2+ with cytoskeletal components may be metabolically significant. The sufficiency of an endwise depolymerization model for describing calcium-induced disassembly was demonstrated by three criteria: (a) correlation of the observed time course of disassembly with the initial polymer length distributi...

Synthetic calcium phosphates, e.g., hydroxyapatite (HAP) and tricalcium phosphate (TCP), are the most commonly used bone-graft materials due to their high chemical similarity natural hydroxyapatite—the inorganic component of bones. Calcium in form a free ion or bound complexes plays key role many biological functions, including bone regeneration. This paper explores possibility increasing Ca2+-...