Calcium phosphate materials (CaPs) are similar to inorganic part of human mineralized tissues (i.e., bone, enamel, and dentin). Owing to their high biocompatibility, CaPs, mainly hydroxyapatite (HA), have been investigated for their use in various medical applications. One of the most widely used ways to improve the biological and physicochemical properties of HA is ionic substitution with trac...

Calcium phosphate precipitation obtained from aqueous solutions at room and body temperature and pH 5.5-7.5 were investigated by high-resolution transmission electron microscopy (HRTEM), transmission electron diffraction, scanning electron microscopy (SEM) and X-ray diffraction (XRD). Supersaturated solutions of calcium phosphates were prepared by different methods of mixing of the stock soluti...

R. Samur, Marmara University, Istanbul, Turkey; L. S. Özyegin, Marmara University, Istanbul; D. Ağaoğulları, Istanbul Technical University, Istanbul; F. N. Oktar, Marmara University, Istanbul; S. Agathopoulos, Ioannina University, Greece; C. Kalkandelen, Istanbul University, Istanbul; İ. Duman, Istanbul Technical University, Istanbul; B. Ben-Nissan, The University of Technology, Sydney, Austral...

Phosphopeptides are among the most interesting biomolecules with characteristic molecular structure and functions. They usually contain clusters of phosphoserines, which can effectively bind calcium and iron, and inhibit formation of insoluble calcium phosphates or iron complexes. Therefore, phosphopeptides can increase calcium or iron bioavailability and prevent lipid oxidation in foods. Milk ...

We tested the hypothesis that increased systemic vascular resistance in spontaneously hypertensive rats may be secondary to enhanced phospholipase C activity in response to vasoconstrictor stimuli. Activation of phospholipase C by angiotensin II (Ang II), thromboxane A2, arginine vasopressin, and endothelin-1 was compared in cultured glomerular mesangial cells and mesenteric vascular smooth mus...

As phosphate derivatives form such important intermediates between the functioning of tissues and the metabolism which supports function, we decided to investigate the levels of certain phosphates in brain slices before and during metabolism in vitro. Investigation of this type appeared all the more necessary because there is now an extremely interesting group of observations on the levels of p...

BACKGROUND LDL, cholesterol, and their oxidized forms are known cardiovascular risk factors and are often found in atherosclerotic lesions of various stages. Little is known, however, about whether they are directly involved in the formation of calcium phosphate compounds. METHODS We used the pH-stat technique to follow the kinetics of calcium phosphate precipitation at pH 7.4, 37 degrees C, ...

1. Rachitic bone lesions may be produced in rats by a diet containing an excess of calcium, but deficient in phosphates. 2. Similar lesions follow a diet deficient in calcium, but containing an excess of phosphates. The endochondral lesions, however, are less pronounced. 3. A diet deficient in both calcium and phosphate induces atypical rickets. 4. Inorganic salts other than calcium or phosphat...