INTRODUCTION Calotropis procera is known to produce contact dermatitis and the latex of this plant produces intense inflammation when injected locally. However, the precise mode of its pro-inflammatory effect is not known. In present study we have pharmacologically characterized the inflammation induced by latex of C. procera in a rat paw edema model and determined the role of histamine in late...

Calotropis procera are widely used traditional medicinal plant to treat various ailments. It is an erect, perennial shrub luxuriantly thriving in wastelands. Plants are the richest sources of bioactive organic chemicals on earth. They are the store house of secondary metabolites such as alkaloids, terpenoids, steroids and flavonoids etc. The traditional medicine involves the use of different pl...