Although we have recently demonstrated that plasma catecholamines induce antiproteolytic effects on skeletal muscle (Graça FA, Gonçalves DAP, Silveira WA, Lira EC, Chaves VE, Zanon NM, Garófalo MAR, Kettelhut IC, Navegantes LCC. Am J Physiol Endocrinol Metab. 305: E1483-E1494, 2013), the role of the muscle sympathetic innervation and, more specifically, norepinephrine (NE) in regulating the ubi...

Richard G. Appel, MD, Department of Internal Medicine/Nephrology, Bowman Gray School of Medicine, Medical Center Boulevard, Winston-Salem NC 27157-1053 (USA) Dear Sir, A number of studies indicate that atrial natriuretic factor (ANF) acts to impair argi-nine vasopressin (AVP)-induced water transport. In the perfused rabbit cortical collecting tubule, ANF inhibited the hydraulic conductivity res...

The nitric oxide (NO)-cGMP signaling system and cAMP system play critical roles in formation of multiple-trial induced, protein synthesis-dependent long-term memory (LTM) in many vertebrates and invertebrates. The relationship between the NO-cGMP system and cAMP system, however, remains controversial. In honey bees, the two systems have been suggested to converge on protein kinase A (PKA), base...

BACKGROUND Ample evidence demonstrates cardiovascular protection by incretin-based therapy using dipeptidyl peptidase 4 inhibitor (DPP4i) and glucagon-like peptide-1 (GLP-1) under either diabetic or nondiabetic condition. Their action on myocardium is mediated by the cyclic AMP (cAMP) signal; however, the pathway remains uncertain. This study was conducted to address the effect of DPP4i/GLP-1/c...

adenylyl cyclase is a membrane-bound enzyme that catalyzes the conversion of atp to camp. the inhibition of adenylyl cyclase was carried out by measuring the ability of the macrophage chemotactic protein-1 to inhibit the torskolin-induced enzyme activity. adenylyl cyclase activity in the presenc of macrophage chemotactic protein-1 was decreased compared to that in controls [2.11+/-0.15 (mean +/...

background- cd24 is a cell adhesion molecule that has been implicated in metastatic tumor progression cells. our aim was clarify correlation between cd24 expression and camp:cgmp ratio in murine colorectal cancer cell line (ct26) after using cholera toxin. materials and methods- the ct26 cells were cultured in microtubes for assaying camp and cgmp; also the cells were cultured in flasks for ass...

Community-based monitoring programs (CBMPs) are a cost-effective option to collect the long-term data required effectively monitor estuaries. Data quality concerns have caused some CBMP datasets, which could fill knowledge gaps for aquatic ecosystems, go unused. The Community Aquatic Monitoring Program (CAMP) is that has collected littoral nekton assemblage from estuaries in southern Gulf of St...

Alpha toxin derived from Clostridium perfringens was used for diagnosis of Streptococcus agalactiae (St.agalactiae) by rapid and spot CAMP tests. The selected Cl.perfringens strain was cultured in optimized conditions; the supernatant of culture was concentrated by ultra filter and purified by DEAE cellulose chromatography. The efficacy of both purified and crude α-toxins were examined by rapid...

Inhibition of bacterial growth under aerobic conditions by elevated levels of cyclic adenosine 3',5'-monophosphate (cAMP), first revealed more than 50 years ago, was attributed to accumulation of toxic methylglyoxal (MG). Here, we report a Crp-dependent mechanism rather than MG accumulation that accounts for the phenotype in Shewanella oneidensis, an emerging research model for the bacterial ph...

kegiatan English camp merupakan salah satu gagasan yang inovatif untuk meningkatkan kepercayaan diri mahasiswa dalam berkomunikasi menggunakan bahasa Inggris. Pengabdian kepada masyarakat ini bertujuan motivasi dan anggota atau pengurus UKM Community of Megarezky (E-COMER) Universitas Makassar berbicara Inggris melalui Camp. Kegiatan outdoor dilakukan sebagai latihan di luar kelas dikenal denga...