نتایج جستجو برای: cancellous bone

تعداد نتایج: 305423  

Journal: :Journal of nutritional science and vitaminology 2007
Jun Iwamoto Azusa Seki Tsuyoshi Takeda Harumoto Yamada Yoshihiro Sato James K Yeh

The beneficial effects of alfacalcidol (ALF) on bone mass, bone formation, and bone resorption have been established in ovariectomized rats. Our previous studies showed that high-dose glucocorticoid (GC) administration (methylprednisolone sodium succinate, 5.0 mg/kg, s.c., 3 times a week) for 4 wk induced cancellous osteopenia without significantly affecting cortical bone mass in Sprague-Dawley...

Journal: :Journal of applied physiology 2010
Maureen E Lynch Russell P Main Qian Xu Daniel J Walsh Mitchell B Schaffler Timothy M Wright Marjolein C H van der Meulen

Mechanical loading can be used to increase bone mass and thus attenuate pathological bone loss. Because the skeleton's adaptive response to loading is most robust before adulthood, elucidating sex-specific responses during growth may help maximize peak bone mass. This study investigated the effect of sex on the response to controlled, in vivo mechanical loading in growing mice. Ten-week-old mal...

Journal: :The Journal of clinical endocrinology and metabolism 1998
T Seck B Scheppach S Scharla I Diel W F Blum H Bismar G Schmid B Krempien R Ziegler J Pfeilschifter

Insulin-like growth factor-I (IGF-I) and -II are important local regulators of bone metabolism, but their role as determinants of human bone mass is still unclear. In the present study, we analyzed the concentration of IGF-I and -II in the bone matrix of 533 human biopsies from the iliac crest that were obtained during surgery for early breast cancer. There was an inverse association of bone ma...

Journal: :The Journal of bone and joint surgery. British volume 2003
M Ding A Odgaard I Hvid

We obtained medial and lateral subchondral cancellous bone specimens from ten human post-mortem proximal tibiae with early osteoarthritis (OA) and ten normal age- and gender-matched proximal tibiae. The specimens were scanned by micro-CT and the three-dimensional microstructural properties were quantified. Medial OA cancellous bone was significantly thicker and markedly plate-like, but lower in...

2010
Ian H. Parkinson Danielle Forbes Peter Sutton-Smith Nicola L. Fazzalari

High-resolution micro computed tomography has enabled measurement of bone architecture derived from 3D representations of cancellous bone. Twenty-eight vertebral bodies were obtained from four embalmed male cadavers. From 3D anaglyphs, trabecular rod thickness and length were measured and the trabecular rod Buckling index was calculated. From 3D voxel-based datasets, bone volume density, trabec...

Journal: :Endocrinology 1997
J M Cavolina G L Evans S A Harris M Zhang K C Westerlind R T Turner

A 14-day orbital spaceflight was performed using ovariectomized Fisher 344 rats to determine the combined effects of estrogen deficiency and near weightlessness on tibia radial bone growth and cancellous bone turnover. Twelve ovariectomized rats with established cancellous osteopenia were flown aboard the space shuttle Columbia (STS-62). Thirty ovariectomized rats were housed on earth as ground...

Journal: :The Journal of bone and joint surgery. British volume 1990
G C Bannister S K Young A S Baker J G Mackinnon P A Magnusson

Bleeding from cancellous bone causes lamination within bone cement and at its prosthetic interfaces, and weakens the fixation of joint replacements. We examined the effects of anaesthesia and blood pressure on bleeding in human cancellous bone, and investigated the local response to freezing saline, 1:200,000 adrenaline and hydrogen peroxide. Spinal anaesthesia reduced cancellous bleeding by an...

Journal: :Bone 2007
S Y Tang U Zeenath D Vashishth

Post-translational modifications of collagen, such as non-enzymatic glycation (NEG), occur through the presence of extracellular sugars and cause the formation of advanced glycation end-products (AGEs). While AGEs have been shown to accumulate in a variety of collagenous human tissues and alter the tissues' functional behavior, the role of AGEs in modifying the mechanical properties of cancello...

Journal: :Journal of applied physiology 2010
Hisataka Kondo Kenji Yumoto Joshua S Alwood Rose Mojarrab Angela Wang Eduardo A C Almeida Nancy D Searby Charles L Limoli Ruth K Globus

Exposure of astronauts in space to radiation during weightlessness may contribute to subsequent bone loss. Gamma irradiation of postpubertal mice rapidly increases the number of bone-resorbing osteoclasts and causes bone loss in cancellous tissue; similar changes occur in skeletal diseases associated with oxidative stress. Therefore, we hypothesized that increased oxidative stress mediates radi...

2014
Roberto Tarantino Pasquale Donnarumma Cristina Mancarella Marika Rullo Giancarlo Ferrazza Gianna Barrella Sergio Martini Roberto Delfini

Study Design Prospective cohort study. Objectives To analyze the effectiveness and practicality of using cancellous bone substitute with platelet-rich plasma (PRP) in posterolateral arthrodesis. Methods Twenty consecutive patients underwent posterolateral arthrodesis with implantation of cancellous bone substitute soaked with PRP obtained directly in the operating theater on the right hemifield...

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