Patients with stable disease (SD) following cancer treatment have traditionally not been considered responders. We, and others, have previously shown that SD is an important response criteria in cancer patients treated with HD IL-2 immunotherapy [1-5]. Here we summarize findings from 13 sites, including 97 mRCC and 170 mM patients enrolled in the retrospective cohort of a national HD IL-2 datab...

the male breast cancer (mbc) is a very rare neoplasm which accounts for 0.5-1% of the total cases of breast cancer. bilateral involvement is reported to occur in fewer than 2% of all the diagnosed cases of mbc, and synchronous tumors are very rare. because of its rarity, little is known about mbc etiology, its clinical findings and treatment. most patients present with a painless breast mass. t...

The previous story It is surprising that although clear reports were given in the pilot work of Ferguson and colleagues, 1 Farthing and colleagues , 2 and others about 20 years ago, coeliac disease (CD) has not yet gained popularity among obstetricians. In the subsequent two decades, many epidemiological studies clearly showed that it is a very common disease, that it aVects women more than men...

Background Patients with idiopathic inflammatory myopathies (IIMs) are at increased risk of cancer, particularly in the first ±3 years disease, and a cancer stratification was proposed recently [1] , to improve screening IIMs. Objectives The aim our retrospective study determine frequency, temporal relations, types, as well evaluate performance tool well-defined IIM cohort. Methods We analyzed ...

background: minimal bright red bleeding per rectum (mbrbpr) is a common complaint in adult patients. most studies have not been performed in patients with strictly minimal brbpr, and there are no evidence-based recommendations for this group of patients. materials and methods: patients with complaints as small amounts of red blood after wiping or a few drops of blood in the toilet bowl after de...

background : the age standardized incidence rates of esophageal cancer in women and men in iran have the fifth and eighth ranks, respectively. due to the high incidence rate of esophageal cancer and the necessity of knowledge of its geographical distribution, the incidence of this cancer was mapped at province and county levels in the present study. methods: the study population of this empiric...