نتایج جستجو برای: cancers geroprotective

تعداد نتایج: 91117  

2018
Adrian Schmidt Antoinette Monn Elisabeth Schmidt-Weiss Mathias Schmid Beatrix Boesch

First, patients may always develop a second severe illness, even a second cancer. Second, things are not always as they are expected to be. So, careful diagnosis is mandatory. Third, morphology is very important, but sometimes misleading. Always be aware of morphological variants!

2011
Emad Y. Moawad

Considerable research is aimed at determining the mechanism by which tumor cures, or regrows or second cancer develops, to be predictable and controllable. The wide range of doses, from low to very high, estimated statistically is responsible for such risks. A mathematical model is presented that describes both: the growth due to lower or over irradiated doses or the post therapy relapse of hum...

Journal: :international journal of epidemiologic research 2015
parisa chamanparaa abbas moghimbeigi javad faradmal jalal poorolajal

background and aims: the aim of this study was the modeling of the incidence rates of colorectal, breast and prostate cancers using a shared component model in order to explore the spatial pattern of their shared risk factors (i.e., obesity and low physical activity) affecting on cancer incidence, and also to estimate the relative weight of these shared components. methods: in this study, the ...

2016
Alexander Aliper Aleksey V. Belikov Andrew Garazha Leslie Jellen Artem Artemov Maria Suntsova Alena Ivanova Larisa Venkova Nicolas Borisov Anton Buzdin Polina Mamoshina Evgeny Putin Andrew G. Swick Alexey Moskalev Alex Zhavoronkov

Populations in developed nations throughout the world are rapidly aging, and the search for geroprotectors, or anti-aging interventions, has never been more important. Yet while hundreds of geroprotectors have extended lifespan in animal models, none have yet been approved for widespread use in humans. GeroScope is a computational tool that can aid prediction of novel geroprotectors from existi...

Journal: : 2022

Chokeberry contains a wide range of biologically active substances with potential geroprotective activity. An ethanolic extract chokeberry ×Sorbaronia mitschurinii (ABE) has previously been found to have positive effect on the lifespan Drosophila melanogaster individuals in short-term exposure (two weeks). The present study evaluated effects ABE integrity D. intestinal barrier. This indicator i...

Journal: :iranian journal of radiation research 0
f. mohagheghi faculty of medicine, arak university of medical sciences, arak, iran m. mohammadi department of medical physics, faculty of medicine, hamadan university of medical sciences, hamadan, iran

background: the presence of small intestine in the radiation field during pelvic cancers treatment causes an interruption in radiotherapy. a non-invasive method was developed to exclude small intestine during conventional radiotherapy. materials and methods: the incidence of the radiation therapy interruption is highly dependent upon the area of the small intestine included in the portals and i...

Journal: :iranian journal of public health 0
ahmad naghibzadeh-tahami vahid yazdi feyzabadi narges khanjani ahad ashrafi-asgarabad hosniyeh alizaeh vahid reza borhaninejad

background: colorectal cancers (crcs) including colon, rectum and anal cancers are the third most prevalent cancers in the world. there are strong evidence showing the risk of the cigarette smoking, alcohol use, low physical activity and some types of diets in crcs; however, few studies explored the relationship between opium use and crcs. this study aimed to investigate the association between...

2017
Anna Leonov Anthony Arlia-Ciommo Simon D. Bourque Olivia Koupaki Pavlo Kyryakov Pam鼳la Dakik M鼳lissa McAuley Younes Medkour Karamat Mohammad Tamara Di Maulo Vladimir I. Titorenko

We have previously found that exogenously added lithocholic acid delays yeast chronological aging. We demonstrated that lithocholic acid enters the yeast cell, is sorted to mitochondria, resides in both mitochondrial membranes, changes the relative concentrations of different membrane phospholipids, triggers changes in the concentrations of many mitochondrial proteins, and alters some key aspec...

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