Results 69 pts (47 years, male 69%, SAPS II 33, mechanical ventilation 92%) developed 77 episodes (M 44, V 32). Neurosurgical diseases were trauma (39%), meningeal hemorrhage (20%), intracerebral hemorrhage (17%), intracranial tumor (12%). Cerebrospinal fluid leakage was present in 25%, ventriculostomy in 35% (catheter permanence 6.2 days), subdural catheter in 30% (catheter permanence 4.2 days...

Candida glabrata is an opportunistic fungal pathogen that can cause severe invasive infections and can evade phagocytic cell clearance. We are interested in understanding the virulence of this fungal pathogen, in particular its oxidative stress response. Here we investigated C. glabrata, Saccharomyces cerevisiae and Candida albicans responses to two different oxidants: menadione and cumene hydr...

Maria Candida Ribeiro Parisi, Daniel Giannella, Tulio Diniz Fernandes, Karla Freire Rezende, Marcia Nery I Endocrinology Unit, Faculdade de Medicina da Universidade de São Paulo, SP, Brazil. II Gastroenterology Unit, Faculdade de Medicina da Universidade de São Paulo, SP, Brazil. III Orthopaedic Department, Faculdade de Medicina da Universidade de São Paulo, SP, Brazil. IV Medical Specialties C...

BACKGROUND Superficial fungal infections are caused by dermatophytes, yeasts or filamentous fungi. They are correlated to the etiologic agent, the level of integrity of the host immune response, the site of the lesion and also the injured tissue. OBJECTIVE The purpose of this study is to isolate and to identify onychomycosis agents in institutionalized elderly (60 years old +). METHODS The ...

Candida and Aspergillus spp. are the most common agents responsible for invasive fungal infections in children. They are associated with a high mortality and morbidity rate as well as high health care costs. An important increase in their incidence has been observed during the past two decades. In infants and children, invasive candidiasis is five times more frequent than invasive aspergillosis...

INTRODUCTION Spontaneous peritonitis, especially spontaneous fungal peritonitis (SFP), is an important and potentially fatal complication in patients with endstage liver disaese. We evaluated potential risk factors, microbiological findings, and outcome of patients with SFP compared to spontaneous bacterial peritonitis (SBP) in critically ill patients. METHODS Retrospective analyses of critic...

Development of potentially life-threatening enterocolitis is the most frequent complication in children with Hirschsprung disease (HSCR), even after definitive corrective surgery. Intestinal microbiota likely contribute to the etiology of enterocolitis, so the aim of this study was to compare the fecal bacterial and fungal communities of children who developed Hirschsprung-associated enterocoli...