In the title compound, C(11)H(14)N(2)O(5), the nitro group is approximately coplanar with the benzene ring, making a dihedral angle of 4.26 (17)°. The dihedral angle between the methyl-carbamate group and the benzene ring is 72.47 (6)°. There is a strong inter-molecular N-H⋯O hydrogen bond between the N and O atoms from adjacent methyl-carbamate groups, forming a one-dimensional network along t...

Catalytic hydrogenolysis of Z-Gly-NH2 and Z-Ala-NH2 resulted in the corresponding free amides and carbamate salts. This observation is a further experimental proof that carbamic acid derivatives are intermediates of hydrogenolytic removal of carbobenzoxy group under neutral conditions. The ratio of the formation of the two compounds is dependent on the solvent, concentration and chemical struct...

The tetrahydroazepine-annulated [3]ferrocenophane carbamate (4) was synthesized by two different linear routes starting from the readily available α-dimethylamino[3]ferrocenophane-ortho-carbaldehyde rac-6. The carbamate directed lithiation of 4 resulted in a selective attack at a (Cp)C-H bond at the higher substituted "lower" [3]ferrocenophane Cp-ring to eventually yield the respective ester (1...

The clinical severity and toxicodynamics vary according to the agent, the route of absorption, and whether the exposure was intentional. Regardless of these factors, the toxicologic mechanism of acetylcholinesterase (AChE) inhibition remains consistent. The end result is an excess of the neurotransmitter acetylcholine (ACh), which results in overstimulation of muscarinic and nicotinic receptors...

Single crystals for two polymorphs of the ammonium carbamate self-derivative salt of prolinamide have been successfully obtained and characterized. Decarbonation of the carbamate salts was monitored by calorimetry, confirming stabilization of the reactive carbonated adducts in the solid state. Sublimation of the salts afforded crystals of prolinamide, leading to the first crystal structure of t...