نتایج جستجو برای: carbamylation
تعداد نتایج: 238 فیلتر نتایج به سال:
The definition of posttranslational modification (PTM) encompasses a wide group of chemical reactions that allow modification and modulation of protein functions. The regulation of PTMs is crucial for the activity and survival of the cells. Dysregulation of PTMs has been observed in several pathological conditions, including rheumatoid arthritis (RA). RA is a systemic autoimmune disease primari...
OBJECTIVE Carbamylation is part of the aging process and causes adverse changes in structure function proteins. Lipoproteins are subjected to carbamylation. We investigated usefulness carbamylated HDL as a prognostic indicator survival patients with type 2 diabetes association mortality outcomes. RESEARCH DESIGN AND METHODS Baseline plasma was measured by ELISA cohort 1,517 diabetes. The primar...
Reviewing the reaction of potassium cyanate, an antisickling agent, with alpha-amino groups of hemoglobin, it was found that the reaction was a slow process and requires a large excess of the reagent. The reason for the slow reaction rate of carbamylation of hemoglobin by cyanate is that cyanate itself does not react with hemoglobin. It is rather isocyanic acid, the reactive species, that react...
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