5(6)-carboxy-rhodamine 110 isomers were rapidly synthesized by condensation of 3-aminophenol and trimellitic anhydride using microwave irradiation as heating method. after esterification of the two isomers, separation and hydrolyzation provided target products,5-carboxy-rhodamine 110 and 6-carboxy-rhodamine 110, in high yields. the results shows microwave irradiation can effectively reduce the ...