Latar belakang: Indonesia menduduki peringkat pertama angka perokok laki-laki usia produktif antara 20-40 tahun yaitu sebesar 70,5%. Kebiasaan merokok mempunyai dampak yang buruk terhadap kesehatan dan juga dapat berpengaruh pada kadar hemoglobin. Beberapa penelitian menyatakan bahwa ditemukan karbon monoksida mengikat hemoglobin disebut carboxyhemoglobin. Dimana carboxyhemoglobin adalah suatu ...

SUMMARY The effects of increased carboxyhemoglobin levels caused by smoking nonnicotine cigarettes upon exercise-induced angina were investigated in 10 patients. The mean carboxyhemoglobin level after smoking eight nonnicotine cigarettes, one every 30 minutes, rose from 1.58 to 7.79%. Smoking significantly decreased the mean exercise time from the onset of exercise until the onset of angina fro...

Coburn's differential equation for the uptake of carbon monoxide by hemoglobin and two particular types of solution of this equation were considered and the solutions verified for a group of healthy adults consisting of 73 nonsmoking pedestrians or car passengers exposed to low levels of carbon monoxide as experienced in the city of Lyon. The CO levels at the breathing level and the walking spe...

Exposure to carbon monoxide (CO) is the leading cause of death by poisoning in industrialized countries. It accounts for hundreds of accidental deaths and thousands of intentional deaths annually in the United States. CO is a colorless, odorless gas that is easily absorbed through the lungs when inhaled. It competes with oxygen for binding to hemoglobin, but because hemoglobin has an affinity f...

We used an automated four-wavelength spectrometer to measure the concentration of total hemoglobin, percent oxyhemoglobin, carboxyhemoglobin, and methemoglobin, and concentration of oxygen bound to hemoglobin in the blood of humans, dogs, and baboons under clinical and various experimental conditions. Measurements of total hemoglobin and methemoglobin with this simple method were comparable to ...

A study of male and female office workers found no sex difference in the relationship between carboxyhemoglobin (COHb) levels and daily consumption of cigarettes. However, women smoked fewer cigarettes on the average than men. The study found that the COHb levels in smokers were higher among the sedentary office workers than among physically active meat porters and that both had higher levels o...

Intraoperative early detection of anemia, identifying toxic levels of carboxyhemoglobin after carbon monoxide exposure and titrating drug dosage to prevent toxic levels of methemoglobin are important goals. The pulse oximeter works by illuminating light into the tissue and sensing the amount of light absorbed. The same methodology is used by laboratory hemoglobinometers to measure hemoglobin co...

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OBJECTIVES Although carbon monoxide poisoning is a major medical emergency, the armamentarium of recognized prognostic biomarkers displays unsatisfactory diagnostic performance for predicting cumulative endpoints. METHODS We performed a retrospective and observational study to identify all patients admitted for carbon monoxide poisoning during a 2-year period. Complete demographical and clini...

The reaction between carboxyhemoglobin and reduced microperoxidase (MP): Hb4(CO)4 + 4MP=Hb4 + 4MPCO, recently reported by us, has been further studied. By generating species Hb4(CO), Hb4(CO)2, and Hb(CO)3 in the stopped flow cuvette by the reaction of dithionite with the species of the general formula Hb4(O2)x(CO)y(x + y=4) in the presence of microperoxidase it has been possible to determine th...