To generate a good carrier for gene transfection, O-carboxymethyl chitosan-graft-branched polyethylenimine (OCMPEI) copolymers were synthesized by increasing the weight percentage of branched polyethylenimine conjugated to the carboxyl groups of O-carboxymethyl chitosan. These spherical polyplexes with plasmid deoxyribonucleic acid (pDNA) or small interfering ribonucleic acid (siRNA) had diamet...

OBJECTIVE The aim of this study is to evaluate CMC physical-chemical alterations after thermal sterilization and its efficacy in preventing poststernotomy pericardial adhesions. METHODS After autoclaving thermal sterilization, thermal sterile Carboxymethyl Chitosan (CMCts) was submitted to physical-chemical analysis. Twelve animals were divided into two groups and underwent pericardiotomy and...

A facile, efficient, and eco-friendly approach for the preparation of uniform silver nanoparticles (Ag NPs) was developed. The synthesis was conducted in an aqueous medium exposed to microwave irradiation for 8 min, using laboratory-prepared, water-soluble quaternized carboxymethyl chitosan (QCMC) as a chemical reducer and stabilizer and silver nitrate as the silver source. The structure of the...

Iron oxide (Fe3O4) nanoparticles with average sizes of 10 nm were synthesized by a chemical coprecipitation method in the presence of chitosan. Chitosan as a natural polymer which can be extracted from crustaceans was used in the synthesis process in order to achieve more dispersed nanoparticles. Also, chitosan was used to obtain functionalized magnetic nanoparticles for using in different area...

Presently, most nanofiltration membranes are prepared with non-biodegradable petrochemical materials. This process is harmful to the ecosystem and consumes a large amount of non-renewable energy. In this study, biodegradable and biocompatible antibacterial cellulose/chitosan nanofiltration membranes (BC/CS-NFMs) were fabricated and characterized for their mechanical strength, antimicrobial acti...

In the present study, two nanoparticles including lactose myristoyl carboxymethyl chitosan (LMCC) and algal polysaccharide myristoyl carboxymethyl chitosan (AMCC), were obtained for hepatic-targeted Adriamycin (ADM) drug delivery systems. ADM was successfully loaded into the LMCC or AMCC nanoparticle by dialysis. The release function and liver targeting of the nanoparticles was explored, and it...