background: in view of high prevalence of gi cancers in lorestan province, western iran, and a large number of esophageal cancer patients in this region, this study was done to determine the frequency of various gi cancers in the area. â  methods: in a cross-sectional study, all patients from lorestan province for whom endoscoppy and colonoscopy were performed and biopsy was provided entered ou...

We report a 60-year-old woman with intramucosal adenocarcinoma arising in the interposed colon, 40 years after the esophageal reconstruction for lye induced esophageal stricture. Although synchronous adenomas were also found in the native colon where the graft was taken, the number of adenomas was greater in the interposed colon and more dysplastic, even progressed to adenocarcinoma, than that ...

Adenosquamous carcinoma colon is a rare neoplasm of colon and is said to have an aggressive course and thus poorer prognosis. Here we have described a case of adenosquamous carcinoma colon in an elderly female patient, presenting with typical features of a colonic malignancy, but with a rapidly deteriorating clinical course and liver metastasis.

Background: Gastrointestinal Cancers are one of the most important causes of mortality of patients in the world as well as in our country. The North of Iran is in Asian belt of esophagus cancer in addition, in other areas of our country gastric cancer is the most common GI Cancer. Because GI Cancers are common in Lorestan, we decided to study them in patients undergo endoscopy and colonoscopy i...

The newly purified extracellular polysaccharides (exopolysaccharides) from Parachlorella kessleri (PCEPS) were evaluated on their antitumor and immunomodulatory effects in cell culture and mouse colon carcinoma peritoneal dissemination model. In two-dimensional cell culture, the PCEPS treatment inhibited cell growth of both murine and human colon carcinoma cells in a dose- and time-dependent ma...

Thirteen adherent human non-lymphocyte cell lines were tested for their susceptibility to infection by human immunodeficiency virus. Productive infection could be demonstrated in three of five colorectal carcinoma cell lines examined; the other eight human non-lymphocyte cell lines were uninfectible. A susceptible colon carcinoma cell line (HT29), as well as normal colonic mucosa, was shown to ...

Management of locally advanced colon cancer metastases is challenging and operation carries an increased risk of morbidity and mortality. The knowledge of exact sites of involvement can aid the surgeon to make a decision regarding complete resection or palliative therapy. PET/CT scan is an advantage in this setting because metabolic alterations often precede the anatomic changes; moreover, it c...

In an attempt to generate antibodies which recognize novel tumor-associated antigens we have immunized Rhesus monkeys (Macaca mulatta) with human colon carcinoma cells prepared from freshly excised tumors. Immunohistochemical characterization of polyclonal antisera from one monkey (DF6) revealed preferential reactivity with primary and metastatic colon carcinoma tissue, and a general lack of re...

Human glioma (U-118 MG, U-251 MG) and human colon carcinoma (HT-29) spheroids and monolayers were continuously exposed to amiloride under physiological Na+ and HCO3- conditions. Amiloride in concentrations of 0.1-0.2 mM inhibited growth, while 0.5 mM or higher induced disintegration of the glioma spheroids within 4-6 days. Growth retardation of the HT-29 spheroids was achieved at concentrations...

Adequate surgery performed in an early stage of the disease offers the best chance for cure in carcinoma of the right colon. It is generally agreed that right colectomy is the preferred method of treatment under these circumstances. This operation can be utilized with a reasonable risk, particularly if the resection is performed precisely in one stage with immediate anastomosis by suture (Harve...