نتایج جستجو برای: cardiac morphology
تعداد نتایج: 418278 فیلتر نتایج به سال:
The left atrial appendage (LAA) is an extension of the atrium (LA) and has complex anatomical structure unique pathophysiological properties. LAA functions as a decompression chamber during ventricular (LV) systole under increased pressure conditions. Despite previously being considered relatively insignificant portion cardiac anatomy, been highlighted important involved in genesis thrombus for...
Differentiation cultures of embryonic stem (ES) cells can be a useful in vitro system for understanding cardiac myocyte development. However, cell morphometry, sarcomere development, and functional cell-cell junction formation have not been examined in detail to determine whether ES cell-derived cardiac myocytes exhibit structural and functional characteristics similar to cardiac myocytes withi...
Background In conventional cardiac MRI, respiratory effects are suspended or counteracted to avoid artifacts. However, in many disease states, such as pericardial tamponade/constriction and diastolic dysfunction, it is precisely variations in cardiac morphology/function with respect to respiratory changes that reflect the pathophysiology and should be studied. In this work, we image the heart d...
BACKGROUND The diffuse nature of cardiac allograft vasculopathy makes early detection of the disease by traditional noninvasive methods or coronary angiography difficult. The aim of this study was to determine if there is a relation between abnormalities in vessel wall morphology, as assessed by intracoronary ultrasound, and a decreased vasodilatory response to the endothelium-dependent vasodil...
BACKGROUND/AIMS The zebrafish is an emerging model system for the study of cardiac electrophysiology and human arrhythmias. High resolution imaging techniques are powerful tools for the study of zebrafish cardiac electrophysiology, but these methods require the complete absence of cardiac contraction. Many pharmacological agents that uncouple cardiac contraction also markedly alter the cardiac ...
Cardiac hypertrophy is often initiated as an adaptive response to haemodynamic stress or myocardial injury, and allows the heart to meet an increased demand for oxygen. Although initially beneficial, hypertrophy can ultimately contribute to the progression of cardiac disease, leading to an increase in interstitial fibrosis and a decrease in ventricular function. Metabolic changes have emerged a...
Oxidized cholesterols (oxycholesterols) in food have been recognized as strong atherogenic components, but their tissue distributions and roles in cardiovascular diseases remain unclear. To investigate whether accumulation of oxycholesterols is linked to cardiac morphology and function, and whether reduction of oxycholesterols can improve cardiac performance, domestic male swine were randomized...
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