et al. Impact of viability and scar tissue on response to cardiac resynchronization therapy in ischaemic heart failure patients. Eur Heart J 2007;28:33–41. 36. Chalil S, Stegemann B, Muhyaldeen SA, Khadjooi K, Foley PW, Smith RE et al. Effect of posterolateral left ventricular scar on mortality and morbidity following cardiac resynchronization therapy. Pacing Clin Electrophysiol 2007;30: 1201–9...

Cardiac resynchronization therapy is an established treatment modality in heart failure. Though non-response is a serious issue. To address this issue, a good understanding of the electrical activation during left bundle branch block, biventricular, as well as right- and left ventricular pacing is needed. This way by interpreting the 12-lead electrocardiogram, possible reasons for suboptimal tr...

This report described an 81-year-old woman with severe symptomatic heart failure, reduced ejection fraction, mitral regurgitation, and an electrocardiographic QRS width of 118 ms who had ventricular dyssynchrony identified by echocardiographic tissue synchronization imaging. Because of her severe heart failure symptoms on maximal medical therapy, referral to implant a defibrillator, and mechani...

UNLABELLED There have been numerous studies focusing on the assessment of left ventricular mechanical dyssynchrony. These studies are diverse in their purposes, which include more effectively predicting the response to cardiac resynchronization therapy, improving the guidance of the left ventricular lead position, and better prediction of outcome in patients with heart failure. This article rev...

Cardiac resynchronization therapy (CRT) has become a mainstay of heart failure treatment. Since heart failure is a disease primarily affecting older patients it is important to evaluate the performance of CRT in this population. Elderly has been suggested as a subgroup less likely to benefit from CRT. This is an important issue that should be clarified, because most patients with heart failure ...

Cardiol 2003;42:2109–2116. 71. Leclercq C, Walker S, Linde C, Clementy J, Marshall AJ, Ritter P, Djiane P, Mabo P, Levy T, Gadler F, Bailleul C, Daubert JC. Comparative effects of permanent biventricular and right-univentricular pacing in heart failure patients with chronic atrial fibrillation. Eur Heart J 2002;23: 1780–1787. 72. Young JB, Abraham WT, Smith AL, Leon AR, Lieberman R, Wilkoff B, ...

BACKGROUND Even with optimal pharmacotherapy, symptomatic heart failure is associated with substantial morbidity and mortality. PURPOSE To determine the efficacy and safety of cardiac resynchronization therapy in adults with advanced systolic heart failure. DATA SOURCES The Cochrane Central Register of Controlled Trials (2002, volume 4), MEDLINE (1980-2003), EMBASE (1980-2003), other electr...

Background—In heart failure patients with left ventricular dyssynchrony, contractility in delayed segments does not fully contribute to end-systolic function. We quantified this reserve of contraction related to mechanical dyssynchrony to predict response to cardiac resynchronization therapy by the strain delay index, which was defined as the sum of the difference between peak and end-systolic ...

trials and criteria for identifying the appropriate patient. Rev Cardiovasc Med 2003;4:S30–S37. 12. Reuter S, Garrigue S, Barold SS et al. Comparison of characteristics in responders versus non-responders with biventricular pacing for drug resistant heart failure. Am J Cardiol 2002;89:346–350. 13. Tournoux FB, Alabiad C, Fan D et al. Echocardiographic measures of acute haemodynamic response aft...