BACKGROUND Acute rheumatic fever (ARF) remains the leading cause of acquired heart disease in children worldwide. No therapeutic agent has been shown to alter the clinical outcome of the acute illness. Immunological mechanisms appear to be involved in the pathogenesis of ARF. Intravenous immunoglobulin (IVIG), a proven immunomodulator, may benefit cardiac conditions of an autoimmune nature. We ...

OBJECTIVES Acute rheumatic fever (ARF) continues to affect millions of children in developing countries. Aim of the present study was to evaluate the role of myocardial dysfunction in the genesis of heart failure in patients with rheumatic carditis. There are limited studies on this subject. METHODS AND RESULTS In this prospective study, 108 consecutive patients of ARF were evaluated by echoc...

thirty four patients with rheumatic fever arc studied on ward ;} of pahlavi hospital with a view to finding out their serum enzyme levels. five cases had obvious rheumatic carditis who showed raised sgot and serum aldolase. the cases with minimal evidence of carditis, clinic.ally or eicctrocani•iographi., cally, had only slight! serum enzyme elevation

Acute rheumatic fever (ARF) may have different clinical manifestations in different countries according to the genetic predisposition, prevalence of rheumatogenic strains, social and economic conditions. The purpose of this study was to determine the clinical characteristics of ARF in Western Ukraine and to improve the detection of the cases. A retrospective analysis of 85 medical clinical case...

Abstract Background Lyme carditis is a rare and potentially fatal manifestation of disease. Although disease nationally notifiable, data on specific clinical manifestations are not collected systematically. We sought to use novel syndromic surveillance query identify patients with in New York State (excluding City) during 2017-2021. Methods Using the National Syndromic Surveillance Program’s Bi...

Lyme disease is caused by the spirochete Borrelia burgdorferi and is carried to human hosts by infected ticks. There are nearly 30,000 cases of Lyme disease reported to the CDC each year, with 3-4% of those cases reporting Lyme carditis. The most common manifestation of Lyme carditis is partial heart block following bacterial-induced inflammation of the conducting nodes. Here we report a 45-yea...

BACKGROUND Recent data have suggested that cardia biopsy specimens may be more reflective of gastro-oesophageal reflux disease (GORD) than squamous biopsy specimens. AIMS To assess the distribution, severity, and types of mucosal injury in GORD. PATIENTS Thirty patients with symptomatic GORD with no or minimal erosions. METHODS Biopsies were performed at the squamocolumnar junction (Z-lin...

Patients with acute rheumatic fever (ARF) admitted to a tertiary hospital in Ankara between January 1999 and July 2002 were studied cross-sectionally to verify the clinical profile and were followed during the acute period. All patients were investigated for throat culture, streptococcal serologic study, C-reactive protein, and erythrocyte sedimentation rate, and telecardiograms, electrocardiog...