The toluene-degrading strain Rhodococcus opacus PWD4 was found to hydroxylate D-limonene exclusively in the 6-position, yielding enantiomerically pure (+) trans-carveol and traces of (+) carvone. This biotransformation was studied using cells cultivated in chemostat culture with toluene as a carbon and energy source. The maximal specific activity of (+) trans-carveol formation was 14.7 U (g of ...

A convergent, stereocontrolled route to either antipode of the cell adhesion inhibitor, peribysin E, has been achieved from carvone. Highlights of the synthesis include a Diels-Alder reaction to generate a cis-decalin framework, followed by semipinacol-type ring contraction to secure the stereochemistry of the C7 quaternary center. Potential mechanistic pathways for the critical ring contractio...

Nine monoterpenoids related to carvone and seven glucosides were isolated from the water-soluble portion of the methanolic extract of the caraway (fruit of Carum carvi L.), and their structures were clarified by spectral investigation. Among them, eight monoterpenoids and six glucosides were new.

Carvol and carvone are oxidation products from the natural product limonene. They important raw materials for flavours fragrances industry also act as pharmaceutical active ingredients. Orange waste peels possibly represent an attractive source limonene, but studies on valorizing orange peel wastes rare. In this study, we report a new enzymatic cascade system in-situ conversion of limonene into...

The oil obtained by the hydro-distillation method from the fresh leaves and stems of Anethum sowa L. (Dill) herb was analyzed by GC-MS. Nine compounds were isolated and identified. The major constituents were limonene (83 %), grandisol (7.4 %), bis-1,2-benzenedicarboxylic acid (5.7 %), carvone (1.5 %), thujyl alcohol (0.7 %), βphellandrene (0.6 %), cyclohexane (0.5 %), β-myrcene (0.3 %) and α-t...

This study was conducted to assess the effects of irrigation and plant growth promoting bactera on seed yield and qualitative characteristics of Black cumin (Nigella sativa L.) at the Experimental Station of the Research Institute of Forest and Rangeland, Damavan region, Iran. A split-plot experimental design, based on Randomized Complete Block Design (RCBD) with three replications, was used. I...

the aim of this study was to assess the effect of several doses of spearmint essential oil (seo; 0, 250, 500, 750 or 1,000 µg ml-1 buffered rumen fluid) on the fermentation kinetic and digestibility using in vitro gas production technique. a total mixed ration (30% roughage: 70% concentrate) was incubated with buffered rumen fluid. in vitro gas production, asymptotic gas production (a), rate of...

The effects of chiral fragrances (enantiomers of limonene and carvone) on the human autonomic nervous system (ANS) and on self-evaluation were studied in 20 healthy volunteers. Each fragrance was administered to each subject by inhalation using an A-A-B design. Individuals were tested in four separate sessions; in one session one fragrance was administered. ANS parameters recorded were skin tem...

Two convenient methodologies have beendescribed for the enantiospecific synthesis of (–)-valeranone 1. The hydrindanone 12, obtained from the readily andabundantly available monoterpene (R)-carvone,has been converted into the ketoaldehyde 16via the alkene 15b. In anotherdirection the lactone 18, obtainedfrom the hydrindanone 12, has beenelaborated into the ketoaldehyde 16employing two methodolo...