Objective: To analyze the genetic polymorphisms of the cytochrome P450 family and their relationship with squamous cell carcinoma of the oral cavity, pharynx and larynx. Methods: We present a narrative literature review, conducted in Pubmed, Lilacs and Cochrane Databases of articles published in the last five years correlating genetic polymorphisms of the cytochrome P450 family and cancer risk ...

• Travel and thrombosis are associated. Four case-control studies [1-4] and five cohort and randomized controlled studies [5-9] have clearly established that thrombosis is associated with travel. In the four case-control studies, 11.8% of patients with venous thromboembolism had a history of recent travel, by air or other means of transportation, compared to 6.3% of controls with an odds ratio ...

An elevated risk of lung cancer associated with lower levels of body mass index (BMI) has been reported in previous studies.1-9 However, the interpretation of the association between low BMI and lung cancer is complicated by the fact that weight loss may be a sign of smoking. In general, smokers tend to be lighter than non-smokers,1, 10-15 and it is believed that nicotine is responsible for the...

One of the major issues in predicting state failure is the relatively rare occurrence of event onset. This class skew problem can cause difficulties in both estimating a model and selecting a decision boundary. Since the publication of King and Zeng’s (2001) study, scholars have utilized case-control methods to address this issue. This paper re-analyzes the landmark research of the Political In...

Recent evidence suggests that certain Fc gamma receptor (FcγR) alleles are genetic risk factors for infectious diseases. In this study, we evaluated FcγRIIa polymorphism in patients with brucellosis. In a casecontrol study, the frequency of two alleles and three genotypes for FcγRIIa were measured by PCR in 150 patients with brucellosis and 125 healthy controls. The H131 and R131 alleles were f...

Introduction Germline polymorphisms in several genes important to the pathogenesis of prostate cancer have been associated with an increased incidence of disease. A recently identified tumor suppressor gene, PTEN/MMAC1/TEP1, may also have an important role in prostate carcinogenesis and progression. Previous reports have demonstrated frequent loss of PTEN expression in localized prostate cancer...

Background. Human papillomavirus (HPV) infection, especially high-risk HPV16, is a risk factor for cervical cancer. HPV16 genotype demographic variations may affect carcinogenicity. mutations and DNA concentration were examined in cancer development Dhi-Qar province, Iraq. Aim of the study. The study endeavors to elucidate profile correlation between highrisk human type 16 susceptibility Provin...

background: cholecystitis is one of the major digestive diseases. its prevalence is particularly high in some populations. significant risk factors associated with cholecystitis include age, sex, obesity, diet, parity and type 2 diabetes. objective: to determine the association between hla-drb1 and cholecystitis. methods: this casecontrol study included forty iraqi arab patients who had cholecy...