As early as 1910, it was observed in Paris, France, that about 80% of patients with cancer of the oesophagus and cardiac region of the stomach were alcoholics, who drank mainly absinthe (Lamy, 1910). ln the first half of this century, it was also noted from mortality statistics in various countries that high risks for cancers of the oral cavity, pharynx, oesophagus and larynx occurred among per...

The xeroderma pigmentosum group C (XPC) gene plays a significant role in DNA damage recognition during nucleotide excision repair process. Polymorphisms of the XPC gene have been analyzed in numerous casecontrol studies to evaluate bladder cancer risk attributed to XPC genetic variation; however, published data on the association between XPC rs2228001 A/C and bladder cancer risk are inconclusiv...

Aim. To study the dynamics and pattern of publications in Russian on post-COVID-19 syndrome (PCS) order to assess completeness information identify medical specialties with its most active investigation Russia. Material methods . The search for was carried out database largest digital scientific library Russia Elibrary.ru from February 1, 2021 2022. included publicly available consequences coro...

This case-control study examined whether DNA aneuploidy in colorectal adenomas is a risk factor for subsequent ademona recurrence. Cases (recurrent polyp formers) were defined as persons with diagnoses of new adenomas at 2 colonoscopies following the index (first) adenoma diagnosis; controls were persons with no new adenomas at a follow-up at least 1 year after the index diagnosis. Cases (n = 2...

Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disease characterized by the production of a wide range of autoantibodies, resulting in tissue damage. Although the susceptibility to SLE has been attributed to complex interactions between genetic and environmental factors, the influence of a genetic predisposition to SLE is supported by observations of familial aggregations. Fam...

Previous studies had researched the relationship between rs9642880 gene polymorphism and bladder cancer risk, but the results remained unclear. The comprehensive meta-analysis was performed to clarify this possible association. Relevant articles were searched from Pubmed, Embase and web of science. Odds ratios (ORs) and corresponding 95% confidence intervals (CIs) were calculated to assess the ...

The rapid increase followed by a leveling off in the incidence of non-Hodgkin lymphoma (NHL) in the United States and Europe in the last half of the 20th century4,5 has largely remained unexplained, a situation that has fascinated and frustrated a generation of lymphoma researchers. This state of affairs is likely due in part to a multifactorial etiology and the heterogeneous nature of this mal...

The role of Helicobacter pylori infection in gastric cancer was evaluated in a high-risk population in Venezuela using serological assays in a study of 302 cases and 483 neighborhood controls. To investigate the claim that assays for H. pylori should use antigens derived from local strains, four different assays derived from Venezuelan and European strains were used. Prevalence of IgG H. pylori...