Expression of the Xenopus Xcad-1 and Xcad-2 genes initiates during early gastrulation exhibiting a dorsoventral asymmetry in their domains of transcription. At mid-gastrulation the ventral preference becomes stronger and the caudal genes take up a posterior localization in their expression, which they will maintain until their downregulation along the dorsal midline. Comparison of the three Xen...

results first needle placement without imaging resulted in blood return in 1/199 participants and positive epidurography in 179/199 (90%). minimal needle repositioning resulted in a positive epidurogram in the remaining 19 attempts. no intravascular injection patterns were observed. conclusions this compares favorably to published success rates of fluoroscopically-guided technique and was well ...

Type II collagen mutations have been identified in a phenotypic continuum of chondrodysplasias that range widely in clinical severity. They include achondrogenesis type II, hypochondrogenesis, spondyloepiphyseal dysplasia congenita, spondyloepimetaphyseal dysplasia, Kniest dysplasia, and Stickler syndrome. We report here results that define the underlying genetic defect and consequent altered s...

In intact adult vertebrates, muscles can be activated with a high degree of specificity, so that even within a single traditionally defined muscle, groups of motor units can be differentially activated. Such differential activation might reflect detailed control by descending systems, potentially resulting from postnatal experience such that activation of motor units is precisely tailored to th...

30 In intact adult vertebrates, muscles can be activated with a high degree of specificity, so that even 31 within a single traditionally defined muscle, groups of motor units can be differentially activated. Such 32 differential activation might reflect detailed control by descending systems, potentially resulting from 33 postnatal experience such that activation of motor units is precisely ta...

Backgrounds: Hypohidrotic ectodermal dysplasia (HED) is a rare genetic disorder, distinguished by hypotrichosis, hypohidrosis, and hypodontia. HDE can be inherited in X-linked recessive manner as a result of mutations in the ectodysplasin A (EDA) gene as well as autosomal dominant and autosomal recessive manners both of them caused by mutations in EDA receptor (EDAR) and EDAR-associated death d...

conclusions the results show that the analgesic and sedative effects were better when dexmedetomidine was added to bupivacaine than when fentanyl was added or bupivacaine alone was administered in the pediatric population studied here that underwent elective inguinal hernia repair. results a total of 61 patients were analyzed. the lowest pain scores were found in the bd group at all time points...