AIM To evaluate the feasibility of detecting duct-dependent congenital heart disease before hospital discharge by using pulse oximetry. DESIGN Case-control study. SETTING A supra-regional referral centre for paediatric cardiac surgery in Sweden. PATIENTS 200 normal term newborns with echocardiographically normal hearts (median age 1.0 d) and 66 infants with critical congenital heart disea...

Background: Iron deficiency is a common problem in patients with cyanotic congenital heart disease (CCHD), but it often underdiagnosed. Cyanotic iron will experience higher morbidity due to symptoms of hyper viscosity. The consequences anemia may manifest either infancy or later. tendency develop metabolic acidosis and hyper-cyanotic attacks exacerbated by relative anemia. This study was perfor...

5 eksen freze operasyonları havacılık, otomotiv ve kalıpçılık sektörlerinde karmaşık yüzeylerin talaşlı imalatında sıklıkla kullanılır. Bütün bu operasyonlarda boyut toleransları ve yüzey kalitesi çok önemlidir. Parçada veya kesici takımda kesme kuvvetleri nedeniyle oluşan esnemeler kabul edilemeyecek parça kalitesine sebep olabilirler. İstenilen kalitenin daha yüksek bir verimlilik ile sağlanm...

Critical congenital heart disease (CCHD) refers to lesions of the cardiovascular system, present at birth, which if left untreated in early infancy, will severely compromise the infant’s well-being and survival. Transposed great arteries, hypoplastic left heart, total anomalous pulmonary venous drainage, coarctation of the aorta, and interrupted aortic arch account for more than 70% of CCHD. Un...

BACKGROUND Health outcomes are improved when newborn babies with critical congenital heart defects (CCHDs) are detected before acute cardiovascular collapse. The main screening tests used to identify these babies include prenatal ultrasonography and postnatal clinical examination; however, even though both of these methods are available, a significant proportion of babies are still missed. Rout...

BACKGROUND The coronary circulation in cyanotic congenital heart disease (CCHD) includes the extramural coronary arteries, basal coronary blood flow, flow reserve, the coronary microcirculation, and coronary atherogenesis. METHODS Coronary arteriograms were analyzed in 59 adults with CCHD. Dilated extramural coronaries were examined histologically in six patients. Basal coronary blood flow wa...

BACKGROUND Although newborn screening for critical congenital heart disease (CCHD) was recommended by the US Health and Human Services Secretary's Advisory Committee on Heritable Disorders in Newborns and Children to promote early detection, it was deemed by the Secretary of the HHS as not ready for adoption pending an implementation plan from HHS agencies. OBJECTIVE To develop strategies for...

The concept of using pulse oximetry (PO) as a screening test to identify newborn babies with critical congenital heart defects (CCHD) before life-threatening collapse occurs has been debated for some time now. Several recent large studies have consistently shown that PO screening adds value to existing screening techniques with over 90% of CCHDs detected. It can also help identify newborn babie...

BACKGROUND AND OBJECTIVE Critical congenital heart disease (CCHD) is endorsed by the US Secretary of Health and Human Services as part of the recommended uniform screening panel for newborns. Although initial recommendations for implementation exist, as states and hospitals have moved forward with implementation of screening, new challenges and areas for additional focus have been identified. T...

OBJECTIVE To establish simultaneous pre- and postductal oxygen saturation nomograms in asymptomatic newborns when screening for critical congenital heart disease (CCHD) at ∼24 hours after birth. METHODS Asymptomatic term and late preterm newborns admitted to the newborn nursery were screened with simultaneous pre- and postductal oxygen saturation measurements at ∼24 hours after birth. The scr...