The neuropoietic cytokine cholinergic differentiation factor/leukemia inhibitory factor (CDF/LIF) acts as a trophic factor, enhancing neuronal survival, and as a differentiation factor, altering neuronal gene expression. There is also evidence that its plays a role in the response of adult neural tissue to injury. We have examined this possibility further in rats by analyzing changes in the lev...

B- myb and cdc25C exemplify different groups of genes whose transcription is consecutively up-regulated during the cell cycle. Both promoters are controlled by transcriptional repression via modules consisting of an E2F binding site (E2FBS) or the related CDE plus a contiguous CHR co-repressor element. We now show that the B- myb repressor module, which is derepressed early (mid G1), is prefere...

• The English Cancer Drugs Fund (CDF) was introduced in 2010 to provide access to cancer drugs not routinely available on the National Health Service (NHS).1 • In its first year (2010/11), the Department of Health allocated £50million to the interim CDF. This has increased to £340million for 2015/16, and its future from April 2016 is uncertain.1 • The criteria for CDF reimbursement relies on th...

P-type (CaV2.1) Ca2+ channels are a central conduit of neuronal Ca2+ entry, so their Ca2+ feedback regulation promises widespread neurobiological impact. Heterologous expression of recombinant CaV2.1 channels demonstrates that the Ca2+ sensor calmodulin can trigger Ca2+-dependent facilitation (CDF) of channel opening. This facilitation occurs when local Ca2+ influx through individual channels s...

BACKGROUND AND PURPOSE Determining cognitive dysfunctioning (CDF) after stroke is an important issue because it influences choices for management in terms of return to previous activities. Because previous research in subacute stroke has shown important variations in CDF rates, we aimed to describe the frequency and neuropsychological profile of CDF in subacute stroke outside dementia. We used ...

BACKGOUND The Cancer Drugs Fund (CDF) has been the subject of controversy since its inception, with critics arguing that it creates a "backdoor" to the National Health Service (NHS), circumventing the National Institute for Health and Care Excellence and its health technology assessment program. Nonetheless, with its creation comes a new decision problem, how to best allocate resources among ca...

and Λb → pK − (CDF). Also examined are branching-fraction measurements or limits for the B0 s → D (∗) s D (∗) s modes (Belle, CDF, and DZero), the B0 s → γ γ radiative penguin decay (Belle), and three two-body charmless B0 s meson decay channels (CDF). Implications for the phenomenology of electroweak and QCD physics, as well as searches for physics beyond the Standard Model, are identified whe...

Using data collected with the CDF Run II detector, new measurements on bottom production cross-sections are presented. The latest achievements in bottom hadron spectroscopy are discussed. The results are based on a large sample of semileptonic and hadronic decays of bottom states made available by triggers based on the precise CDF tracking system. 1 First Observation of the Baryons Σb and Σ ∗ b...

PATIENT Female, 16 FINAL DIAGNOSIS: Malrotation and cholecystoduodenal fistula Symptoms: Abdominal pain • anorexia • fever • nausea • vomiting MEDICATION - Clinical Procedure: - Specialty: Gastroenterology and Hepatology. OBJECTIVE Anatomical anomaly/variation. BACKGROUND Cholecystoduodenal fistula (CDF) is the most common cholecystenteric fistula. It is a late complication of gallbladder...

The Collider Detector at Fermilab (CDF) records proton-antiproton collisions at center of mass energy of 2.0 TeV at the Tevatron collider. A new collider run, Run II, of the Tevatron started in April 2001. Increased luminosity will result in about 1 PB of data recorded on tapes in the next two years. Currently the CDF experiment has about 260 TB of data stored on tapes. This amount includes raw...