THIS ISSUE of the American Journal of Physiology-Cell Physiology begins the publication of a series of theme reviews focused on adaptive responses to cellular hypoxia. The original conception of this series came from AJP-Cell Physiol Associate Editor Michael Goligorsky, who kindly invited me to serve as guest editor and has assisted me in bringing his concept to publication. The maintenance of ...

ABSTRACT First Person is a series of interviews with the first authors selection papers published in Journal Cell Science, helping researchers promote themselves alongside their papers. Franziska Lehne author on ‘ Swip-1 promotes exocytosis glue granules exocrine Drosophila salivary gland’, JCS. conducted research described this article while PhD student Prof. Dr Sven Bogdan's lab at Institute ...

Abstract Cell-based high content imaging has become a versatile and powerful method for studying e. g. cellular viability, morphology or physiology. However, its various applications require complex as well expensive hardware consumables, limiting utility usability. To broaden the applicability of cell-based imaging, we have developed tools assaying techniques being exemplary portrayed in this ...

The quiescence, rounding, sinking of the granules, and paling of the nucleus are similar to the effects seen after the injection of potassium and sodium chloride (11). Since the sodium salts of the anions were used, it might be inferred that the sodium is the active agent in the injected solutions. This is not entirely the case, however, for the effective concentrations of NaCl required are man...

The effects of hyperbaric stress on the morphology of Saccharomyces cerevisiae were studied in batch cultures under pressures between 0.1 MPa and 0.6 MPa and different gas compositions (air, oxygen, nitrogen or carbon dioxide), covering aerobic and anaerobic conditions. A method using automatic image analysis for classification of S. cerevisiae cells based on their morphology was developed and ...