We report 2 cases of disseminated cryptococcosis with central nervous system involvement in patients with chronic lymphoid malignancies occurring within 1 month of starting on ibrutinib. Characteristically, in both cases, no inflammation was seen in the cerebrospinal fluid. Central nervous system mycoses should be considered as a potential complication of ibrutinib.

background : labeling, gathering mutual information, clustering and classification of central nervous system tumors may assist in predicting not only distinct diagnoses based on tumor-specific features but also prognosis. this study evaluates the epidemi- ological features of central nervous system tumors in children who referred to mahak’s pediatric cancer treatment and research center in tehr...

polyomaviruses may cause human disease, particularly in immunocompromised hosts. jcv, one of the members of polyomaviridae family, is the causative agent of the neurological disease progressive multifocal leukoencephalopathy (pml), which occurs mostly in immunocompromised patients. progressive multifocal leukoencephalopathy (pml) is a progressive demyelinating disorder of the central nervous sy...

Polyomaviruses may cause human disease, particularly in immunocompromised hosts. JCV, one of the members of polyomaviridae family, is the causative agent of the neurological disease progressive multifocal leukoencephalopathy (PML), which occurs mostly in immunocompromised patients. Progressive Multifocal leukoencephalopathy (PML) is a progressive demyelinating disorder of the central nervous sy...

how to cite this article: khoddami m, akbarzadeh a, mordai a, bidari zerehpoush f, alipour h, samadzadeh s, alipour b.diagnostic accuracy of frozen section of central nervous system lesions: a 10-year study. iran j child neurol. 2015 winter;9(1):25-30.   abstract objective definitive diagnosis of the central nervous system (cns) lesions is unknown prior to histopathological examination. to dete...

Background and Objectives: Gliomas are the most prevalent subgroup of primary brain tumors with a relatively high mortality. However, oligodendrogliomas have a better prognosis compared to other subtypes due to their sensitivity to chemotherapy. Considering the low incidence and the resulting lack of information about oligodendrogliomas, particularly i...

A major problem for neuroscientists and clinicians is why the central nervous system shows ineffective regeneration after injury. Injured peripheral nerve fibers reform their connections, whereas those in injured spinal cord never re-grow. Insights into the mechanisms for repair and restoration of function after spinal cord injury have been obtained by experiments showing that injured nerve cel...