Coronary-subclavian steal (CSS) can occur after coronary artery bypass grafting (CABG) using the internal thoracic artery (ITA). Subclavian artery (SA) stenosis proximal to the ITA graft causes CSS. We describe a technique for cardiac and cerebral protection during endovascular stenting for CSS due to right SA origin stenosis after CABG. A 64-year-old man with a history of CABG using the right ...

Selective antegrade cerebral perfusion (SACP) for aortic arch surgery has evolved considerably since it was first reported. Various pressure rates have been investigated through animal models, as has the effect of warmer perfusate temperatures and hematocrit. Clinical research into pH management, the role of unilateral and bilateral perfusion, and core temperatures have further refined the proc...

Citation: Lyu M, Cui Y, Zhao T, Ning Z, Ren J, Jin X, Fan G and Zhu Y (2018) Tnfrsf12a-Mediated Atherosclerosis Signaling and Inflammatory Response as a Common Protection Mechanism of Shuxuening Injection Against Both Myocardial and Cerebral Ischemia-Reperfusion Injuries. Front. Pharmacol. 9:312. doi: 10.3389/fphar.2018.00312 Tnfrsf12a-Mediated Atherosclerosis Signaling and Inflammatory Respons...

Metabolic suppression may have a role in cerebral protection. It is often assumed that the cerebral metabolic and protective effects of qualitative burst suppression are similar to those of the isoelectric encephalogram (EEG). We have examined the effect of different degrees of EEG suppression on blood flow and oxygen difference during general anaesthesia. We studied 11 patients undergoing gene...

It is essential to select the optimum method of cerebral protection and operative technique for arch repair to improve the surgical outcome of arch aneurysm or dissection. Selective antegrade cerebral perfusion (SACP) is our current method of choice if required cerebral protection time exceeds 30 minutes. Moderate hypothermic two-arch vessel perfusion (innominate artery or right axillary artery...

BACKGROUND AND PURPOSE Purinergic nucleoside inosine elicits protection and regeneration during various injuries. The purpose of this study was to examine the protective effects of inosine against cerebral ischemia. METHODS Adult Sprague-Dawley rats were anesthetized. Inosine, hypoxathine, or vehicle was administered intracerebroventricularly before transient right middle cerebral artery occl...