Spinal cord injury is a devastating chronic condition resulting in temporary or permanent motor,sensory or autonomic dysfunction of the cord. The manifestation of spinal cord injury based onthe severity and involved areas could be different. Numerous studies have demonstrated thatbradycardia, hypotension, and orthostatic hypotension are present insignificant number ofpat...

1. Lenehan B, Fisher CG, Vaccaro A, Fehlings M, Aarabi B, Dvorak MF. The urgency of surgical decompression in acute central cord injuries with spondylosis and without instability. Spine (Phila Pa 1976) 2010;35 21 Suppl: S180‐6. 2. Del Bigio MR, Johnson GE. Clinical presentation of spinal cord concussion. Spine (Phila Pa 1976) 1989;14:37‐40. 3. Kawano O, Ueta T, Shiba K, Iwamoto Y. Outcome of de...

acute injuries of the spine and spinal cord are among the most causes of severe disability and death after trauma. data about spine fracture with or without cord damage are different. the aim of this study was to determine epidemiology and demographics of spinal injury in main trauma center, guilan, an iranian province. the present study was a descriptive study of all cases of traumatic spine i...

Introduction Conventional magnetic resonance imaging (MRI) is the best imaging modality to demonstrate ligamentous injury, hematoma, disk herniation, spinal cord edema and hemorrhage that occur following trauma. Quantitative and qualitative image parameters like lesion length, maximum spinal cord compression, spinal cord swelling and, presence of hemorrhage within the cord has been reported to ...

The degenerative spinal cord disease cervical spondylotic myelopathy (CSM), and caused by trauma, can result in debilitating symptoms affecting quality of life. This study used acupotomy other Korean medicine treatments (acupuncture, herbal medicine, physical therapy) to improve the CSM myelopathy. visual analog scale, modified Japanese Orthopaedic Association scale (mJOA scale), Nurick grading...

After spinal cord injury, transected axons fail to regenerate, yet significant, spontaneous functional improvement can be observed over time. Distinct central nervous system regions retain the capacity to generate new neurons and glia from an endogenous pool of progenitor cells and to compensate neural cell loss following certain lesions. The aim of the present study was to investigate whether ...

BACKGROUND AND PURPOSE Acute markers of spinal cord injury are essential for both diagnostic and prognostic purposes. The goal of this study was to assess the relationship between early MR imaging biomarkers after acute cervical spinal cord injury and to evaluate their predictive validity of neurologic impairment. MATERIALS AND METHODS We performed a retrospective cohort study of 95 patients ...

M anagement of patients with an acute cervical spinal cord injury in an intensive care unit or similar monitored setting is recommended. • Use of cardiac, hemodynamic, and respiratory monitoring devices to detect cardiovascular dysfunction and respiratory insufficiency in patients following acute spinal cord injury is recommended. • Correction of hypotension in spinal cord injury (systolic bloo...

Background: Following spinal cord injury, reactive astrocytes upregulate chondroitin sulfate proteoglycans (CSPGs) which act as a barrier to neuronal repair and regeneration. Therefore, enzymatic digestion of CSPGs by chondroitinase ABC (cABC) is a key strategy in the treatment of spinal cord injury. Furthermore, cABC has been shown to attenuate post spinal cord injury inflamma...

Clinically-relevant animal cervical spinal cord injury (SCI) models are essential for developing and testing potential therapies; however, producing reliable cervical SCI is difficult due to lack of satisfactory methods of vertebral stabilization. The conventional method to stabilize the spine is to suspend the rostral and caudal cervical spine via clamps attached to cervical spinous processes....