Cervical biopsies were taken from women with abnormal Papanicolaou smears and from normal women serving as con trols, using the colpomicroscope as an aid in localizing lesions on the exposed portion of the cervix. Half of each biopsy was processed for light microscopy, and the other half was proc essed for both phase contrast and electron microscopy. The fine structure of dysplasia and carcinom...

OBJECTIVE This study was undertaken to evaluate knowledge of cervical dysplasia and human papillomavirus (HPV) among women seen in a colposcopy clinic. STUDY DESIGN Demographics, knowledge, and psychological distress were assessed in structured interviews with 175 women before, during, and after colposcopy. RESULTS Respondents had low knowledge scores before and after colposcopy; however, t...

Cervical biopsies were taken from women with abnormal Papanicolaou smears and from normal women serving as con trols, using the colpomicroscope as an aid in localizing lesions on the exposed portion of the cervix. Half of each biopsy was processed for light microscopy, and the other half was proc essed for both phase contrast and electron microscopy. The fine structure of dysplasia and carcinom...

The cytological investigation is a subjective method which does not allow to determine accurately the morphological changes of the epithelium cells, therefore additional diagnostic methods must be used. Such a method is the Quantitative DNA Analysis. We used the obtained results for statistical processing in order to deternime whether there is a significant difference between the cell populatio...

(CIN II), and severe dysplasia or carcinoma in situ (CIN III), depend ing upon the extent of nuclear abnormality and the degree to which the differentiated upper layers of the epithelium are replaced by abnormal cells (8). The lesions differ from cancer in that the abnormal cells are confined to the epithelium and do not transgress the basement mem brane beneath it. Both cervical dysplasia and ...

High-grade dysplasia induced by high-risk types of human papillomavirus (HPV) precedes invasive cancer in anal squamous epithelium just as it does in the cervix. A therapeutic HPV vaccine strategy as a potential treatment for anal dysplasia was tested in a standard Phase I dose escalation trial. The primary objective was to evaluate the safety of the agent; additional study aims were to evaluat...

Background Cancer cervix is a major health problem in India, accounting for 26.1-43.8% of all cancers in Indian women. Dysplasia on Pap smear has been reported in 15-40% of HIV positive women which is 10-11 times higher than those observed among HIV negative women. Patients with persistent inflammatory Pap smears harbor high proportion of HPV infection and cervical intraepithelial neoplasia (20...

Ichthyosis uteri is a rare condition in which the entire surface of the endometrium is replaced by stratified squamous epithelium. Though the condition often is considered as benign, anaplastic and dysplastic changes have been reported. We describe herein a rare case of low-grade squamous cell carcinoma of endometrium associated with extensive ichthyosis uteri with dysplasia. The cervix showed ...