We describe a high-performance liquid chromatographic procedure for the simultaneous measurement of vitamins K1 and E in human serum. Delipidated human serum (free of vitamins K1 and E) was used to make standard solutions of these vitamins, and cetyl naphthoate and alpha-tocopheryl acetate were the internal standards for vitamin K1 and vitamin E, respectively. A simple, novel separation method ...

Animals dosed orally with nitrite (1.5 X 10(-3) mol/kg) and nonyl dimethylbenzylammonium bromide (2.9 X 10(-4) mol/kg) exhibit liver damage within two hours; cetyl trimethylammonium bromide plus nitrite was not significantly hepatotoxic. Both nonyl dimethylbenzyl ammonium bromide and cetyl trimethylammonium bromide were demethylated by rat-liver microsomal preparations; substrate concentrations...

BACKGROUND Recently there has been a remarkable surge of interest about natural products and their applications in the cosmetic industry. Topical delivery of antioxidants from natural sources is one of the approaches used to reverse signs of skin aging. The aim of this research was to develop a nanoemulsion cream for topical delivery of 30% ethanolic extract derived from local Phyllanthus urina...

Surfactants are indisputably more important today, in terms of their use industry and daily life, as well the tasks they perform. In recent years, due to driving force environmental concerns, orientations alternatives surfactants that cause less or no harm environment have accelerated. One these trends is synthesis alkyl polyglycosides (APG) detergent industry. this study, different acidic cata...

Extended-release matrix tablets of diltiazem hydrochloride (DTZ) were prepared using waxy materials alone or in combination with Kollidon SR. Matrix waxy materials were carnauba wax (CW), bees wax (BW), cetyl alcohol (CA) and glyceryl monostearate (GMS). Dissolution studies were carried out by using a six stations USP XXII type 1 apparatus. The in vitro drug release study was done in 1000 ml ph...

Lamellar gel networks based on mixtures of cetostearyl alcohol and a cationic surfactant, cetyl-trimethylammonium chloride, were studied using combination rheometry optical coherence tomography (OCT) velocimetry. Experiments conducted in stress-controlled rheometer with parallel plate geometry. Each formulation was found to exhibit yield stress thixotropy. The shear start-up behavior response c...