The global regulator Lrp plays a central role as both a repressor and an activator in Pap phase variation. Unlike most other members of the Lrp regulon such as ilvIH, activation of papBA transcription requires the coregulator PapI and is methylation dependent. We developed a two-color genetic screen to identify Lrp mutations that inhibit Pap phase variation but still activate ilvIH transcriptio...

Crude methanolic extracts and fractions from the aerial parts of seven species of Hypericum (H. caprifoliatum Cham. and Schltdl., H. carinatum Griseb., H. connatum Lam., H. ternum A. St.-Hil., H. myrianthum Cham. and Schltdl., H. piriai Arechav. and H. polyanthemum Klotzsch ex Reichardt) growing in southern Brazil were analyzed for their in vitro antifungal activity against a panel of standardi...

Three new cecidogenous species of Palaeomystella Fletcher (Lepidoptera, Momphidae) from the Brazilian Atlantic Rain Forest are described. Larvae of P. fernandesi Moreira & Becker, sp. n., P. rosaemariae Moreira & Becker, sp. n. and P. tavaresi Becker & Moreira, sp. n. induce galls, respectively, on Tibouchina sellowiana (Cham.) Cogn., T. asperior (Cham.) Cogn. and T. fissinervia (Schrank & Mart...

The IBM BlueGene/L (BG/L) super-computer holds 3 of the top 10 rankings on the 26th TOP500 list of LINPACK performance. The system is novel in its design in many aspects when compared to other more traditional high-performance computing systems. When developing system libraries as well as when tuning application code for BG/L it is essential to be able to measure the impact of code modification...

BACKGROUND Recent analyses show that donor funding for child health is increasing, but little information is available on actual costs to deliver child health care services. Understanding how unit costs scale with service volume in Malawi can help planners allocate budgets as health services expand. METHODS Data on facility level inputs and outputs were collected at 24 health centres in four ...

In previous papers we have addressed the problem of deriving from an architectural description pieces of information useful to drive testing [2, 3]. Our approach is based on the use of the CHAM formalism for architectural descriptions, in the way proposed by [5]. In this paper we provide a new method for the analysis and testing of a software architecture. It consists of modeling a software arc...

The aim of this in vitro study was to evaluate, using the photoelastic analysis method, the stress distribution in mandibular bone surrounding a bar-clip overdenture when 2 implant angulations were simulated. Two mandibular photoelastic models were manufactured, with 2 implants embedded in the interforaminal region: model 1-PAPI, a photoelastic analysis model with parallel implants; and model 2...

Streptomyces albus J1074-pAPI (Streptomyces albus-pAPI) is a recombinant strain constructed to biotechnologically produce apigenin, flavonoid with interesting bioactive features that up now has been manufactured by extraction from plants long and not environmentally friendly procedures. So far, in literature, only maximum apigenin concentration of 80.0 µg·L?1 obtained shake flasks. In this pape...