Twenty-six patients being evaluated for renovascular hypertension were studied to assess the diagnostic value of enhancing the differential between renal venous renins (PRA) by a single 25 mg oral dose of converting enzyme inhibitor (CEI, captopril). Antihypertensive medications were not discontinued prior to the study, and renal venous effluent was sampled before and 30 minutes after CEI. Eigh...

In six inbred dogs with neonatally-induced coarctation hypertension, and in seven littermate controls, acute responses of proximal arterial pressure and plasma renin activity (PRA) to converting enzyme inhibitor (CEI; SQ 20,881, 0.5 mg/kg i.v.) were serially examined. Studies were performed at 2, 6, and 12 months post-aortic banding under sodium-replete and -deplete conditions. Both in normoten...

In six inbred dogs with neonatally-induced coarctation hypertension, and in seven littermate controls, acute responses of proximal arterial pressure and plasma renln activity (PRA) to converting enzyme inhibitor (CEI; SQ 20,881, 0.5 rag/kg i.v.) were serially examined. Studies were performed at 2, 6, and 12 months post-aortic banding under sodium-replete and -deplete conditions. Both in normote...

Clearance and micropuncture experiments were performed to evaluate the influence of converting enzyme inhibition (CEI) (SQ 14,225) on renal hemodynamics, glomerular filtration rate (GFR), segmental vascular resistances, and superficial nephron function in anesthetized sodium restricted dogs. In one series (n = 8), renal blood flow (RBF) and GFR exhibited a high degree of autoregulatory efficien...

We investigated the effect of converting enzyme inhibition (CEI) on the relationship between renal perfusion pressure (RPP) and steady-state plasma renin activity (PRA) in uninephrectomized conscious dogs on normal-salt (80 meq Na+/day) and low-salt (10 meq Na+/day) diets. Stimulus-response curves for the renal baroreceptor were determined by measuring the steady-state PRA while the RPP was low...

The early blood pressure and hemodynamic effects of the converting enzyme inhibitor (CEI), captopril, were compared in 23 hypertensive patients with those of a specific angiotensin II antagonist (AA), [Sar1, Thr8] A II. AA reduced mean arterial pressure (MAP) greater than 10 mm Hg only in seven of 23 patients vs 15 of 23 who responded to CEI (p less than 0.02). With both drugs, changes in MAP w...

Gioblastoma is one of the most refractory tumors in central nervous system, and the prognosis remains poor. Temozolomide is a first-line agent for newly-diagnosed glioblastoma, but chemotherapy for recurrent or temozolomide-resistant glioblastoma has not been established. To determine whether chemotherapy with carboplatin, oral etoposide, and interferon β (CEI) prolongs survivals of patients be...

BACKGROUND This study aims to investigate differences between continuous epidural infusion (CEI) and programmed intermittent epidural bolus (IEB) analgesia for the Chinese parturients undergoing spontaneous delivery and to approach their safety to parturients and neonates. METHODS Two hundred healthy American Society of Anesthesiologists class I or II, term (≥37 weeks' gestation), nulliparous...

PIEB has been reported as being superior to CEI for labor analgesia. The aim of this study was to measure the pressures generated by two commercially available pumps (CADD PIB, Smiths and Gemstar, Hospira) when delivering PIEB or CEI at 2 commonly used rates of infusion (10 or 5 mL). The two pumps were set to deliver fluid at four rates (CEI: 5 or 10 mL/h; PIEB: 5 or 10 mL every h) and connecte...

background & aims of the study: petrochemical industry is an important industry in the economic development of the country that causes employees have exposure with several kinds of contamination. the aim of this study was semi-quantitative assessment of the health risk of occupational exposure to chemical materials and investigation of spirometry indices between employees of petrochemical indus...