BACKGROUND The purpose of this study was to investigate the impact of treatment with transcatheter arterial chemoembolization on the expression of chemokine receptors on memory T cells around tumor sites in vivo in patients with hepatocellular carcinoma. METHODS Blood samples from the hepatic artery and a peripheral vein were collected from 100 patients with hepatocellular carcinoma before an...

Background and AimsTo validate prognostic performance of the China liver cancer (CNLC) staging system as well to compare these parameters with those Barcelona Clinic Liver Cancer (BCLC) for Chinese hepatocellular carcinoma (HCC) treated transarterial chemoembolization (TACE).

Hepatocellular carcinoma (HCC) is common worldwide and frequently fatal. Despite the availability of potentially curative therapies for localized HCC, most patients have unresectable tumor, either at presentation or recurrence. We reviewed 18 randomized trials investigating hepatic arterial embolization-based therapies. Therapy for unresectable HCC is difficult, both because of advanced stage a...

INTRODUCTION Celiac axis occlusion is a challenging condition when catheterization of the hepatic artery is required for chemoembolization of hepatocellular carcinoma (HCC). As a result, the hepatic artery has to be catheterized through the pancreaticoduodenal arcades (PDA) and the gastroduodenal artery (GDA) from the superior mesenteric artery (SMA) which is a tortuous course with acute angles...

OBJECTIVE The objective of this study was to determine the sequential CT findings of controlled hepatocellular carcinoma (HCC) with main portal vein (MPV) thrombosis with the use of transcatheter arterial chemoembolization and additional intra-arterial cisplatin infusion. MATERIALS AND METHODS From January 2004 to September 2006, 138 patients with HCC invading MPV were referred to the angiogr...

OBJECTIVE To determine the degree of tumor necrosis in surgical specimens of hepatocellular carcinomas treated with microspheres preloaded with doxorubicin and to analyze the relationship between the degree of necrosis and a) morphologic factors and b) imaging biomarkers. MATERIAL AND METHODS We studied the livers of 21 patients who had undergone selective arterial chemoembolization with DC b...

First transcatheter embolization of hepatic artery has been materializing in 1974, in France, for unresectable hepatic tumours. Then, this treatment has become use enough in many countries, especially in Japan, where primary hepatic tumours are very frequent. In this article, we present procedures of interventional endovascular treatment for primary hepatic tumours: chemoembolization, intra-art...

Insulinoma liver metastases are rare because only a minority of insulinomas (10%) is malignant. We report a case of a 54 year-old patient diagnosed with malignant insulinoma with synchronous liver metastases, treated first by systemic chemotherapy by Streptozotocin and 5-Fluorouracil without clinical control of symptoms (hypoglycemia), then by pancreatic resection and seven chemoembolization wi...

BACKGROUND/AIMS To evaluate the long-term outcome of surgical and non-surgical local treatments of patients with hepatocellular carcinoma (HCC). METHODS We stratified a cohort of 278 HCC patients using six independent predictors of survival according to the Vienna survival model for HCC (VISUM-HCC). RESULTS Prior to therapy, 224 HCC patients presented with VISUM stage 1 (median survival 18 ...

PURPOSE We aimed to evaluate the combination of the modified Response Evaluation Criteria In Solid Tumors (mRECIST) and contrast-enhanced ultrasonography (CEUS) as a tool for the assessment of hepatocellular carcinoma treated with transarterial chemoembolization. MATERIALS AND METHODS Forty-seven hepatocellular carcinoma patients (80 target tumors suitable for mRECIST measurements) were studi...