despite multiple published studies reporting result of salvage regimens for relapsed and refractory hodgkin's lymphoma, there are no comparisons of different combinations.a total of 44 patients identified with refractory or relapsed hodgkin's lymphoma were considered eligible for this study. the patients were randomly divided into two groups of 22, one of which were treated with gdp regimen (ge...

objective(s): chemoresistance remains the main causes of treatment failure and mortality in cancer patients. there is an urgent need to investigate novel approaches to improve current therapeutic modalities and increase cancer patients' survival. induction of drug efflux due to overexpression of                  p-glycoproteins is considered as an important leading cause of multidrug resis...

purpose: to evaluate the results of combined chemotherapy and periocular carboplatin injection to control advanced intraocular retinoblastoma (rb). methods: in this prospective interventional case-series, we included 8 eyes of 8 patients with advanced intraocular rb (group c or d in international intraocular retinoblastoma classification, iirc). in these patients, periocular carboplatin was inj...

background: solid tumors may occur in 3% of the patients with chronic myeloid leukemia (cml). in this paper, we presented a case of cml following treatment of colon cancer. case presentation: a 25 year old man was diagnosed of adenocarcinoma of rectosigmoid treated with fluorouracil-based chemotherapy. following relapse, he received florouracil, oxaliplatin and irinotecan during the next year. ...

abstract background tumor lysis syndrome (tls) is an oncologic emergency that results from massive lysis of malignant cells. the incidence of tls depends on the risk factors, such as baseline hyperuricemia, bulky tumor burden, elevated serum ldh, and elevated wbc. the objectives of the present study were to assess frequency of tumor lysis syndrom in children with all in two methods of induction...

background recombinant human erythropoietin (rhuepo) treatment can increase hemoglobin levels and decrease transfusion requirements. this study aims to investigate how blood transfusion influences hemoglobin levels in patients receiving rhuepo for 12 weeks. materials and methods this was a case-control study of 60 patients less than 15 years with anemia and a solid tumor in any location between...

the activity and efficacy of iranian synthesized imidocarb dipropionate (imidorazi) has been tested against babesia ovis infection in experimentally and naturally affected sheep. the results indicated that the drug is effective and could be used for treatment of sheep and goats babesiosis. the effectiveness of imidorazi is also similar to the imizol (imidocarb dipropionate) imported from abroad.

background: massive bone allograft is an option in cases of limb preservation and reconstruction after massive benign and malignant bone tumor resection. the purpose of this study was to analyze the outcome of these procedures at imam reza hospital, mashhad university of medical sciences. methods: in this study, 113 cases have been presented. eleven cases were excluded (patients has a traumatic...

background: regarding nurses' significant role in improving quality of marital life in mastectomy patients and their families, implication of the adaptation model can help nurses reaching this goal. aim: this study aimed to determine effect of an educational-supportive program based on roy this quasi-experimental study was performed on 69 mastectomy patients receiving chemotherapy in 2013 ...